ABIL3_ARATH
ID ABIL3_ARATH Reviewed; 321 AA.
AC Q6NMC6; Q3YIV3; Q3YIV4; Q9FNF1;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Protein ABIL3;
DE AltName: Full=Abl interactor-like protein 3;
DE Short=AtABIL3;
GN Name=ABIL3; OrderedLocusNames=At5g24310; ORFNames=MOP9.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=15659634; DOI=10.1105/tpc.104.027987;
RA Basu D., Le J., El-Din El-Assal S., Huang S., Zhang C., Mallery E.L.,
RA Koliantz G., Staiger C.J., Szymanski D.B.;
RT "DISTORTED3/SCAR2 is a putative Arabidopsis WAVE complex subunit that
RT activates the Arp2/3 complex and is required for epidermal morphogenesis.";
RL Plant Cell 17:502-524(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Carninci P., Hayashizaki Y.,
RA Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA Shinozaki K., Ecker J.R.;
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 33-143, AND VARIANT ASN-135.
RC STRAIN=cv. Ag-0, cv. Bla-10, cv. Cvi-0, cv. Da(1)-12, cv. Gr-3, cv. Ita-0,
RC cv. Kas-1, cv. Kr-0, cv. Landsberg erecta, cv. Lip-0, cv. Lisse, cv. Me-0,
RC cv. Mt-0, cv. Nok-0, cv. Oy-0, cv. Te-0, and cv. Tu-1;
RX PubMed=15911589; DOI=10.1534/genetics.104.036152;
RA Cork J.M., Purugganan M.D.;
RT "High-diversity genes in the Arabidopsis genome.";
RL Genetics 170:1897-1911(2005).
CC -!- FUNCTION: Involved in regulation of actin and microtubule organization.
CC Part of a WAVE complex that activates the Arp2/3 complex (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Binds SCAR. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q6NMC6-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the ABI family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB10397.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY817014; AAW49258.1; -; mRNA.
DR EMBL; AB006701; BAB10397.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED93285.1; -; Genomic_DNA.
DR EMBL; BT011734; AAS49097.1; -; mRNA.
DR EMBL; AK222217; BAD95383.1; -; mRNA.
DR EMBL; DQ132115; AAZ74720.1; -; Genomic_DNA.
DR EMBL; DQ132116; AAZ74721.1; -; Genomic_DNA.
DR EMBL; DQ132117; AAZ74722.1; -; Genomic_DNA.
DR EMBL; DQ132118; AAZ74723.1; -; Genomic_DNA.
DR EMBL; DQ132119; AAZ74724.1; -; Genomic_DNA.
DR EMBL; DQ132120; AAZ74725.1; -; Genomic_DNA.
DR EMBL; DQ132121; AAZ74726.1; -; Genomic_DNA.
DR EMBL; DQ132122; AAZ74727.1; -; Genomic_DNA.
DR EMBL; DQ132123; AAZ74728.1; -; Genomic_DNA.
DR EMBL; DQ132124; AAZ74729.1; -; Genomic_DNA.
DR EMBL; DQ132125; AAZ74730.1; -; Genomic_DNA.
DR EMBL; DQ132126; AAZ74731.1; -; Genomic_DNA.
DR EMBL; DQ132127; AAZ74732.1; -; Genomic_DNA.
DR EMBL; DQ132128; AAZ74733.1; -; Genomic_DNA.
DR EMBL; DQ132129; AAZ74734.1; -; Genomic_DNA.
DR EMBL; DQ132113; AAZ74718.1; -; Genomic_DNA.
DR EMBL; DQ132114; AAZ74719.1; -; Genomic_DNA.
DR RefSeq; NP_197819.2; NM_122337.5. [Q6NMC6-1]
DR AlphaFoldDB; Q6NMC6; -.
DR SMR; Q6NMC6; -.
DR IntAct; Q6NMC6; 3.
DR STRING; 3702.AT5G24310.1; -.
DR iPTMnet; Q6NMC6; -.
DR PaxDb; Q6NMC6; -.
DR PRIDE; Q6NMC6; -.
DR ProteomicsDB; 245085; -. [Q6NMC6-1]
DR EnsemblPlants; AT5G24310.1; AT5G24310.1; AT5G24310. [Q6NMC6-1]
DR GeneID; 832498; -.
DR Gramene; AT5G24310.1; AT5G24310.1; AT5G24310. [Q6NMC6-1]
DR KEGG; ath:AT5G24310; -.
DR Araport; AT5G24310; -.
DR TAIR; locus:2169759; AT5G24310.
DR eggNOG; ENOG502R3IQ; Eukaryota.
DR HOGENOM; CLU_054853_1_0_1; -.
DR InParanoid; Q6NMC6; -.
DR PhylomeDB; Q6NMC6; -.
DR PRO; PR:Q6NMC6; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q6NMC6; baseline and differential.
DR Genevisible; Q6NMC6; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0015630; C:microtubule cytoskeleton; IDA:TAIR.
DR GO; GO:0048364; P:root development; IMP:TAIR.
DR GO; GO:0010090; P:trichome morphogenesis; IMP:TAIR.
DR InterPro; IPR028457; ABI.
DR PANTHER; PTHR10460; PTHR10460; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..321
FT /note="Protein ABIL3"
FT /id="PRO_0000191796"
FT REGION 179..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..294
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 135
FT /note="K -> N (in strain: cv. Ita-0)"
FT /evidence="ECO:0000269|PubMed:15911589"
SQ SEQUENCE 321 AA; 36681 MW; 46452BE2FB967E93 CRC64;
MSAAATMPMP REASNYDEIS MQQSMLFSDS LKDLKNLRTQ LYSAAEYFEL SYTNDEQKQI
VVETLKDYAI KALVNTVDHL GSVTYKVNDF VDEKVDEVAG TELRVSCIEQ RLRMCQEYMD
HEGRSQQSLV IDTPKFHKRY FLPSGEIKRG GNLAKLKNVE GSFDGEDDWN QFRNAVRATI
RETPPPPVRK PILQSPSQRK PQRSATFSFS SIATAPKKEQ DKRAVSPHRF PLLRSGSVAI
RPSSISRPTT PSKSRAVTPT PKRYPSEPRR SASVRVAFEK EAQKEPEHQQ QPSKSKRLLK
ALLSRRKTKK DDTLYTYLDE Y