SULH2_SCHPO
ID SULH2_SCHPO Reviewed; 840 AA.
AC Q9URY8;
DT 29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Probable sulfate permease C869.05c;
GN ORFNames=SPAC869.05c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-823, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- FUNCTION: High affinity uptake of sulfate into the cell. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000305}.
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DR EMBL; CU329670; CAB60015.1; -; Genomic_DNA.
DR PIR; T39116; T39116.
DR RefSeq; NP_595014.1; NM_001020445.2.
DR AlphaFoldDB; Q9URY8; -.
DR SMR; Q9URY8; -.
DR BioGRID; 279562; 13.
DR STRING; 4896.SPAC869.05c.1; -.
DR iPTMnet; Q9URY8; -.
DR MaxQB; Q9URY8; -.
DR PaxDb; Q9URY8; -.
DR PRIDE; Q9URY8; -.
DR EnsemblFungi; SPAC869.05c.1; SPAC869.05c.1:pep; SPAC869.05c.
DR GeneID; 2543130; -.
DR KEGG; spo:SPAC869.05c; -.
DR PomBase; SPAC869.05c; -.
DR VEuPathDB; FungiDB:SPAC869.05c; -.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_8_1_1; -.
DR InParanoid; Q9URY8; -.
DR OMA; CLLIEHI; -.
DR PhylomeDB; Q9URY8; -.
DR Reactome; R-SPO-427601; Multifunctional anion exchangers.
DR PRO; PR:Q9URY8; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0015301; F:anion:anion antiporter activity; IBA:GO_Central.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; ISO:PomBase.
DR GO; GO:1902434; P:sulfate import across plasma membrane; IC:PomBase.
DR Gene3D; 3.30.750.24; -; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR11814; PTHR11814; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SSF52091; 1.
DR TIGRFAMs; TIGR00815; sulP; 1.
DR PROSITE; PS50801; STAS; 1.
PE 1: Evidence at protein level;
KW Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..840
FT /note="Probable sulfate permease C869.05c"
FT /id="PRO_0000080187"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 410..430
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 447..467
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 470..490
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 505..525
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 527..547
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 578..733
FT /note="STAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
FT MOD_RES 823
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 840 AA; 93518 MW; ED4833E162B69077 CRC64;
MRAWGWVRNK FSSEDDYNDG ASNKDYPDRF NEFDNSQNDH NDYTQNNAQF QNAQTTTFGR
TISRVKAYYE IPEDDELDEL ASIPQWFKKN VTSNIFKNFL HYLKSLFPII EWLPNYNPYW
LINDLIAGIT VGCVVVPQGM SYAKVATLPS EYGLYSSFVG VAIYCFFATS KDVSIGPVAV
MSLITAKVIA NVMAKDETYT APQIATCLAL LAGAITCGIG LLRLGFIIEF IPVPAVAGFT
TGSALNILSG QVPALMGYKN KVTAKATYMV IIQSLKHLPD TTVDAAFGLV SLFILFFTKY
MCQYLGKRYP RWQQAFFLTN TLRSAVVVIV GTAISYAICK HHRSDPPISI IKTVPRGFQH
VGVPLITKKL CRDLASELPV SVIVLLLEHI SIAKSFGRVN DYRIVPDQEL IAMGVTNLIG
IFFNAYPATG SFSRSAIKAK AGVKTPIAGI FTAAVVILSL YCLTDAFYYI PNAILSAVII
HAVTDLILPM KQTILFWRLQ PLEACIFFIS VIVSVFSSIE NGIYVSVCLA AALLLLRIAK
PHGSFLGKIQ AANKYGSDNI ANVRDIYVPL EMKEENPNLE IQSPPPGVFI FRLQESFTYP
NASRVSTMIS RRIKDLTRRG IDNIYVKDID RPWNVPRQRK KKENSEIEDL RPLLQAIIFD
FSAVNNLDTT AVQSLIDIRK ELEIYANETV EFHFTNIRSG WIKRTLVAAG FGKPKGHAVD
ASVCVEVAAP LRDANLSAES SRNLSRIITP IYDDEEGNVS GHIYELDGKN NSDLSMHCQK
GSNQVEIEFV EFNSRKYPFF HVDVASAVVD LQHRLLSPQK SDSFGSLKEG GTTTIKKIEN
