ID   SULH3_SCHPO             Reviewed;         667 AA.
AC   O59782;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Probable sulfate permease C320.05;
GN   ORFNames=SPCC320.05;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Possible sulfate transporter.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC       {ECO:0000305}.
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DR   EMBL; CU329672; CAA18307.1; -; Genomic_DNA.
DR   PIR; T41306; T41306.
DR   RefSeq; NP_587724.1; NM_001022719.2.
DR   AlphaFoldDB; O59782; -.
DR   SMR; O59782; -.
DR   BioGRID; 275438; 3.
DR   STRING; 4896.SPCC320.05.1; -.
DR   iPTMnet; O59782; -.
DR   MaxQB; O59782; -.
DR   PaxDb; O59782; -.
DR   PRIDE; O59782; -.
DR   EnsemblFungi; SPCC320.05.1; SPCC320.05.1:pep; SPCC320.05.
DR   GeneID; 2538858; -.
DR   KEGG; spo:SPCC320.05; -.
DR   PomBase; SPCC320.05; -.
DR   VEuPathDB; FungiDB:SPCC320.05; -.
DR   eggNOG; KOG0236; Eukaryota.
DR   HOGENOM; CLU_003182_10_2_1; -.
DR   InParanoid; O59782; -.
DR   OMA; PMGPSAI; -.
DR   PhylomeDB; O59782; -.
DR   Reactome; R-SPO-174362; Transport and synthesis of PAPS.
DR   Reactome; R-SPO-427601; Multifunctional anion exchangers.
DR   PRO; PR:O59782; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; HDA:PomBase.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015301; F:anion:anion antiporter activity; IBA:GO_Central.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015116; F:sulfate transmembrane transporter activity; ISM:PomBase.
DR   GO; GO:1902358; P:sulfate transmembrane transport; ISM:PomBase.
DR   Gene3D; 3.30.750.24; -; 1.
DR   InterPro; IPR011547; SLC26A/SulP_dom.
DR   InterPro; IPR001902; SLC26A/SulP_fam.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   PANTHER; PTHR11814; PTHR11814; 1.
DR   Pfam; PF01740; STAS; 1.
DR   Pfam; PF00916; Sulfate_transp; 1.
DR   SUPFAM; SSF52091; SSF52091; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..667
FT                   /note="Probable sulfate permease C320.05"
FT                   /id="PRO_0000303897"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        336..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        405..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        433..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        465..485
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          532..657
FT                   /note="STAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   667 AA;  73468 MW;  1FA587A0BC27C284 CRC64;
     MSSPSENHLL GPKTSFIDNR TSTSRPLHEI PSYQSLARRS STWKRANIPQ QKPSLVRRIN
     YYIPVLHWLP NYSLRNIIWD VLAGCSTACL SVPIALSFAQ TFLGVPPIYI LTGTAIGPIL
     YCLFTACPLI SIGPEAGMCL LIAENIHQRV LSKADVPQET AILVTGLIAF IAGIINLAAG
     LFRLGFLDAL VSPVLLRGCI LSISMIIMIN QGSVFFGFSG VKYKGSDFPI DKLMFLIRNM
     SKANIYTTIL SCITISLLIG CRNLKSKLSA KYPRIVSIPD AVIILLLGSF LSKKFDWHSN
     YGIAILGEIK TTILLPKLPL PEKNKLHFIT QSLQTGVMCS FLAFIDTVIA VKAISLQTNN
     LIRSNRELIS LGAANIGSSL FCGLPICGGY LRTKCNIMSG ARTQVATIAC SVLILLATFF
     IMPVFSTVPT CMLASMVVSL GVSLFADAAV EIFKLARIRV WWELGIIFSI ATCTMMFGLE
     TGIIFGLSIT VMQIIRHSTR SRIMFRSPTS NGTAEFILED AASTLSHRTN PSSTAVESAP
     RILVVRIPEP LFFANVSQLE DRLNRLEKYG HPRMHPGETP YRRIEDIEVV VFDMVGVSSI
     DSSALFAFQR ILKEYVEHQV EVHLVSLDPQ VLHIFEKHGL LDLIGGYDHV QDSIKKVDAL
     CDIELGV