SULT_ICTPU
ID SULT_ICTPU Reviewed; 18 AA.
AC P82609;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 29-SEP-2021, entry version 48.
DE RecName: Full=Phenol sulfotransferase;
DE EC=2.8.2.1;
DE Flags: Fragment;
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998;
RN [1]
RP PROTEIN SEQUENCE.
RC TISSUE=Intestinal mucosa, and Liver;
RX PubMed=10775429; DOI=10.1006/abbi.2000.1746;
RA Tong Z., James M.O.;
RT "Purification and characterization of hepatic and intestinal phenol
RT sulfotransferase with high affinity for benzo[a]pyrene phenols from channel
RT catfish, Ictalurus punctatus.";
RL Arch. Biochem. Biophys. 376:409-419(2000).
CC -!- FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate
CC (PAPS) as sulfonate donor to catalyze the sulfate conjugation of
CC phenolic compounds.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-
CC bisphosphate + an aryl sulfate + H(+); Xref=Rhea:RHEA:12164,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:33853, ChEBI:CHEBI:58339,
CC ChEBI:CHEBI:58343, ChEBI:CHEBI:140317; EC=2.8.2.1;
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. {ECO:0000305}.
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DR Proteomes; UP000221080; Genome assembly.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004062; F:aryl sulfotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Cytoplasm; Direct protein sequencing; Lipid metabolism; Steroid metabolism;
KW Transferase.
FT CHAIN <1..>18
FT /note="Phenol sulfotransferase"
FT /id="PRO_0000085176"
FT NON_TER 1
FT NON_TER 18
SQ SEQUENCE 18 AA; 2141 MW; D0396EAC30BFC29C CRC64;
SFFEQNXKIV YVARNAKD