SUMO4_ARATH
ID SUMO4_ARATH Reviewed; 114 AA.
AC Q9FKC5;
DT 10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Putative small ubiquitin-related modifier 4;
DE Short=AtSUMO4;
GN Name=SUMO4; Synonyms=SUM4; OrderedLocusNames=At5g48710; ORFNames=K24G6.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Ubiquitin-like protein which can be covalently attached to
CC target lysines as a monomer. Does not seem to be involved in protein
CC degradation and may function as an antagonist of ubiquitin in the
CC degradation process (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with SAE2, SCE1, SIZ1 and MMS21 Covalently attached
CC to a number of proteins. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC -!- MISCELLANEOUS: Stress conditions rapidly and substantially elevates the
CC amount of SUMO1 and SUMO2 conjugates with a concomitant reduction in
CC the amount of free SUMO proteins. The SUMO conjugation system plays an
CC important function in stress protection and/or repair.
CC -!- SIMILARITY: Belongs to the ubiquitin family. SUMO subfamily.
CC {ECO:0000305}.
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DR EMBL; AB012242; BAB09424.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95714.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70103.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70104.1; -; Genomic_DNA.
DR RefSeq; NP_001318763.1; NM_001344800.1.
DR RefSeq; NP_001331738.1; NM_001344801.1.
DR RefSeq; NP_199682.1; NM_124248.2.
DR AlphaFoldDB; Q9FKC5; -.
DR SMR; Q9FKC5; -.
DR STRING; 3702.AT5G48710.1; -.
DR PaxDb; Q9FKC5; -.
DR PRIDE; Q9FKC5; -.
DR EnsemblPlants; AT5G48710.1; AT5G48710.1; AT5G48710.
DR EnsemblPlants; AT5G48710.2; AT5G48710.2; AT5G48710.
DR EnsemblPlants; AT5G48710.3; AT5G48710.3; AT5G48710.
DR GeneID; 834929; -.
DR Gramene; AT5G48710.1; AT5G48710.1; AT5G48710.
DR Gramene; AT5G48710.2; AT5G48710.2; AT5G48710.
DR Gramene; AT5G48710.3; AT5G48710.3; AT5G48710.
DR KEGG; ath:AT5G48710; -.
DR Araport; AT5G48710; -.
DR TAIR; locus:2156509; AT5G48710.
DR eggNOG; KOG1769; Eukaryota.
DR HOGENOM; CLU_148322_4_0_1; -.
DR InParanoid; Q9FKC5; -.
DR OMA; IREYHTL; -.
DR OrthoDB; 1583700at2759; -.
DR PhylomeDB; Q9FKC5; -.
DR PRO; PR:Q9FKC5; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FKC5; baseline and differential.
DR Genevisible; Q9FKC5; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0031386; F:protein tag; IBA:GO_Central.
DR GO; GO:0044389; F:ubiquitin-like protein ligase binding; IBA:GO_Central.
DR GO; GO:0016925; P:protein sumoylation; IBA:GO_Central.
DR InterPro; IPR022617; Rad60/SUMO-like_dom.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR Pfam; PF11976; Rad60-SLD; 1.
DR SUPFAM; SSF54236; SSF54236; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Isopeptide bond; Nucleus; Reference proteome;
KW Ubl conjugation pathway.
FT CHAIN 1..114
FT /note="Putative small ubiquitin-related modifier 4"
FT /id="PRO_0000397035"
FT DOMAIN 26..104
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00214"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CROSSLNK 104
FT /note="Glycyl lysine isopeptide (Gly-Lys) (interchain with
FT K-? in acceptor proteins)"
SQ SEQUENCE 114 AA; 13409 MW; 9D5C8D9154856914 CRC64;
MSTTSRVGSN EVKMEGQKRK VVSDPTHVTL KVKGQDEEDF RVFWVRRNAK LLKMMELYTK
MRGIEWNTFR FLFDGSRIRE YHTPDELERK DGDEIDAMLC QQSGFGPSSI KFRV