SUMV2_CAEEL
ID SUMV2_CAEEL Reviewed; 1145 AA.
AC Q22992;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 2.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Protein sumv-2 {ECO:0000305};
DE AltName: Full=Suppressor of synthetic multivulva protein 2 {ECO:0000312|WormBase:F54D11.2};
GN Name=sumv-2 {ECO:0000312|WormBase:F54D11.2};
GN ORFNames=F54D11.2 {ECO:0000312|WormBase:F54D11.2};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000312|Proteomes:UP000001940};
RN [1] {ECO:0000312|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000312|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2] {ECO:0000305}
RP FUNCTION.
RX PubMed=24882710; DOI=10.1016/j.ydbio.2014.05.018;
RA Yucel D., Hoe M., Llamosas E., Kant S., Jamieson C., Young P.A.,
RA Crossley M., Nicholas H.R.;
RT "SUMV-1 antagonizes the activity of synthetic multivulva genes in
RT Caenorhabditis elegans.";
RL Dev. Biol. 392:266-282(2014).
CC -!- FUNCTION: Influences the activity of genes involved in vulval
CC development. {ECO:0000269|PubMed:24882710}.
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DR EMBL; FO081360; CCD71035.1; -; Genomic_DNA.
DR PIR; T29329; T29329.
DR RefSeq; NP_001256043.1; NM_001269114.1.
DR AlphaFoldDB; Q22992; -.
DR IntAct; Q22992; 1.
DR STRING; 6239.F54D11.2.1; -.
DR ESTHER; caeel-q22992; NLS3-Tex30.
DR EPD; Q22992; -.
DR PaxDb; Q22992; -.
DR PeptideAtlas; Q22992; -.
DR PRIDE; Q22992; -.
DR EnsemblMetazoa; F54D11.2.1; F54D11.2.1; WBGene00018812.
DR EnsemblMetazoa; F54D11.2.2; F54D11.2.2; WBGene00018812.
DR GeneID; 24104625; -.
DR KEGG; cel:CELE_F54D11.2; -.
DR UCSC; F54D11.2.1; c. elegans.
DR CTD; 24104625; -.
DR WormBase; F54D11.2; CE30805; WBGene00018812; sumv-2.
DR eggNOG; KOG3253; Eukaryota.
DR GeneTree; ENSGT00390000007636; -.
DR HOGENOM; CLU_277219_0_0_1; -.
DR InParanoid; Q22992; -.
DR OMA; RIFRWLQ; -.
DR OrthoDB; 536129at2759; -.
DR PRO; PR:Q22992; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00018812; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0044545; C:NSL complex; IBA:GO_Central.
DR GO; GO:0043984; P:histone H4-K16 acetylation; IBA:GO_Central.
DR GO; GO:0043981; P:histone H4-K5 acetylation; IBA:GO_Central.
DR GO; GO:0043982; P:histone H4-K8 acetylation; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR026555; NSL3/Tex30.
DR PANTHER; PTHR13136; PTHR13136; 1.
PE 4: Predicted;
KW Developmental protein; Reference proteome.
FT CHAIN 1..1145
FT /note="Protein sumv-2"
FT /evidence="ECO:0000305"
FT /id="PRO_0000433361"
FT REGION 1..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 999..1025
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1040..1059
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1073..1145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..464
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1102..1138
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1145 AA; 125988 MW; 24665B545306FE82 CRC64;
MKPGRKSLPK KNRASNITEK MPTTSTEAQS SSSKNQDRCR SFSQELGVDD EPEEQQAPVA
TPKQTKKAQK TAKTTEEVKS PRKSARKSEL KKPEPEEKAK EPRKSASKRK SSSLMNKDEP
STSTEAPSAD VPGTSEASDE ASEIQEAPEN PNSALAIKKR LMGGGESSKS APTKNPPKAR
KSNVKKPEKE AEALAPPEPP AEPQEAAETP APEPLVPEKK PKIEDAPTTS SPKKSTPTSA
PPTRASARVS KPNRLYADGS FNTEILGRTR ITEQNPVKEA QAKESTPELA DLPLPAGRRK
STAAPRAPPA PKPIPVINGV LRGYIPSVKV PLAEYEVDGE IINLNEGVNE TMDTILAKVC
EDGVEKHEDI DPKVVKAKKL AKIDYTKRLK LQVKKLDIQM RIKIPSTPEE LGKRKRQAPK
TDDFYWSAQS RTKLKGSSKE REETPAFDEE SPIGGDEKRQ QKARESISHL FDAEMDASIK
EAKKYSVSFD KYIKPKITGA LKHAKIKLMS RKRQSAEPDD FYYHELLVDQ VSPSNSNVEN
VDVDVDIEET DDKVDPTEFE ISEEGVIGIR DEAVDMAEQI ALVIPRPTKH DGSPMSMDEI
QMRAMEHVES RTKCLDGSLE IVLNQLGHEM APPTRGVEEQ GCQWHTVTSA NAQALKNLYT
IANNCTEDAI TWTHQFMIEN LEVHMLASYL SILKYAKRLN SSRFGYVISS TDQLDPEWTQ
VTSLLKSFVY KRHTEPGTEV LNNTIPYHRM TDTVFLLVPP TLTFGDHQRA PPRHHARIFR
WLQSIGHQDS EFISFDEDID ATCSVAEYLS DVIVERICDK VRQKNKYRPN CNVVLVGYGA
STYLIHRAAN LVEGISAIIS IGFPVMTSLG RRGTADDEIL LTYCPTLFIV GAEGRRFNNE
AITELRTSMI SPSGLVVVGH SNDMILVPTS MLLRLGISQT VVFRMVLEKI LDFLNLEPVR
QQEFADLVPI ELNNVFDLDS ALLKSDKALS GLAFASSTHS ASSSAAPSPV GASGRRATVT
GAGSEDIAKR RKESIILSQQ IAAPSISGPP PPAPSPRTED RFLAFQNLVA STITTGDDMP
RRASMGASPR VIERGDFRDH RPPPPPPLPI LQNPVATPMS QQPPLPSPAP PPPRGPVDPA
SISLI
