ID   SUNI_BACSU              Reviewed;         105 AA.
AC   O31989;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Sublancin immunity protein SunI {ECO:0000303|PubMed:19047653};
DE   AltName: Full=SPbeta prophage-derived protein YolF;
GN   Name=sunI {ECO:0000303|PubMed:19047653}; Synonyms=yolF;
GN   OrderedLocusNames=BSU21490;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   FUNCTION, SUBCELLULAR LOCATION, INDUCTION, DISRUPTION PHENOTYPE, AND
RP   TOPOLOGY.
RC   STRAIN=168;
RX   PubMed=19047653; DOI=10.1128/aac.01189-08;
RA   Dubois J.Y., Kouwen T.R., Schurich A.K., Reis C.R., Ensing H.T., Trip E.N.,
RA   Zweers J.C., van Dijl J.M.;
RT   "Immunity to the bacteriocin sublancin 168 is determined by the SunI (YolF)
RT   protein of Bacillus subtilis.";
RL   Antimicrob. Agents Chemother. 53:651-661(2009).
CC   -!- FUNCTION: Is essential and sufficient to confer resistance to the
CC       bacteriocin sublancin 168. {ECO:0000269|PubMed:19047653}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:19047653};
CC       Single-pass membrane protein {ECO:0000305|PubMed:19047653}. Note=A
CC       small amount is also associated with the cell wall, but this is
CC       probably contamination. {ECO:0000269|PubMed:19047653}.
CC   -!- INDUCTION: Expressed during both exponential and post-exponential
CC       growth (at protein level). {ECO:0000269|PubMed:19047653}.
CC   -!- DISRUPTION PHENOTYPE: Loss of resistance to the bacteriocin sublancin
CC       168. {ECO:0000269|PubMed:19047653}.
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DR   EMBL; AL009126; CAB14067.1; -; Genomic_DNA.
DR   RefSeq; NP_390032.1; NC_000964.3.
DR   RefSeq; WP_009967545.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O31989; -.
DR   STRING; 224308.BSU21490; -.
DR   jPOST; O31989; -.
DR   PaxDb; O31989; -.
DR   PRIDE; O31989; -.
DR   DNASU; 939125; -.
DR   EnsemblBacteria; CAB14067; CAB14067; BSU_21490.
DR   GeneID; 939125; -.
DR   KEGG; bsu:BSU21490; -.
DR   PATRIC; fig|224308.179.peg.2346; -.
DR   BioCyc; BSUB:BSU21490-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR   GO; GO:0030153; P:bacteriocin immunity; IDA:UniProtKB.
DR   InterPro; IPR009589; SunI.
DR   Pfam; PF06713; bPH_4; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..105
FT                   /note="Sublancin immunity protein SunI"
FT                   /id="PRO_0000359951"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..105
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305|PubMed:19047653"
SQ   SEQUENCE   105 AA;  12255 MW;  28E04FBC2A9C09A7 CRC64;
     MEYVVMIIIL LALFFIFTVF LNTRYSFDEK CLVLKFGLSK TEIPINQIVS IKESDKYGVA
     DNIDYKIGMP YAQPDRIVIE TTNKRFLVFL NGAQQFIQKY KRVSV