ID   SURF1_ARATH             Reviewed;         354 AA.
AC   Q9SE51; Q9LVH9;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Surfeit locus protein 1;
DE            Short=Surfeit 1;
DE   AltName: Full=Cytochrome c oxidase assembly protein SURF1;
DE   AltName: Full=Protein EMBRYO DEFECTIVE 3121;
DE   AltName: Full=Surfeit locus 1 cytochrome c oxidase biogenesis protein;
GN   Name=SURF1; Synonyms=EMB3121; OrderedLocusNames=At3g17910;
GN   ORFNames=MEB5.13;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Leaf;
RX   PubMed=10622737; DOI=10.1016/s0014-5793(99)01571-9;
RA   Poyau A., Buchet K., Godinot C.;
RT   "Sequence conservation from human to prokaryotes of Surf1, a protein
RT   involved in cytochrome c oxidase assembly, deficient in Leigh syndrome.";
RL   FEBS Lett. 462:416-420(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably involved in the biogenesis of the COX complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SURF1 (TC 3.D.4.8) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB02714.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AF182953; AAF19609.1; -; mRNA.
DR   EMBL; AB019230; BAB02714.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; AEE76023.1; -; Genomic_DNA.
DR   EMBL; BT024740; ABD59078.1; -; mRNA.
DR   RefSeq; NP_566592.1; NM_112672.3.
DR   AlphaFoldDB; Q9SE51; -.
DR   STRING; 3702.AT3G17910.1; -.
DR   PaxDb; Q9SE51; -.
DR   PRIDE; Q9SE51; -.
DR   ProteomicsDB; 228287; -.
DR   EnsemblPlants; AT3G17910.1; AT3G17910.1; AT3G17910.
DR   GeneID; 821310; -.
DR   Gramene; AT3G17910.1; AT3G17910.1; AT3G17910.
DR   KEGG; ath:AT3G17910; -.
DR   Araport; AT3G17910; -.
DR   TAIR; locus:2088510; AT3G17910.
DR   eggNOG; KOG1563; Eukaryota.
DR   HOGENOM; CLU_047737_4_2_1; -.
DR   InParanoid; Q9SE51; -.
DR   OMA; WYSRDVA; -.
DR   OrthoDB; 923657at2759; -.
DR   PhylomeDB; Q9SE51; -.
DR   PRO; PR:Q9SE51; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9SE51; baseline and differential.
DR   Genevisible; Q9SE51; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR   GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR   CDD; cd06662; SURF1; 1.
DR   InterPro; IPR002994; Surf1/Shy1.
DR   InterPro; IPR045214; Surf1/Surf4.
DR   PANTHER; PTHR23427; PTHR23427; 1.
DR   Pfam; PF02104; SURF1; 1.
DR   PROSITE; PS50895; SURF1; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..354
FT                   /note="Surfeit locus protein 1"
FT                   /id="PRO_0000412564"
FT   TRANSMEM        76..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        328..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   354 AA;  39921 MW;  AB4BD6D0BCB3A68C CRC64;
     MATSLSKILT RSNTKRYWCS TTTSISASPS LPKQFWSRHF SAVADSSSSS SAALGSQSSS
     SAPPQENKRG SKWSQLLLFL PGAITFGLGS WQIVRREEKF KTLEYQQQRL NMEPIKLNID
     HPLDKNLNAL EFRRVSCKGV FDEQRSIYLG PRSRSISGIT ENGFFVITPL MPIPGDLDSM
     QSPILVNRGW VPRSWREKSQ ESAEAEFIAN QSTKAKSPSN EPKSWWKFWS KTPVITKEHI
     SAVKPVEVVG VIRGGENPSI FVPSNDPSTG QWFYVDVPAM ARAVGLPENT IYVEDVHEHV
     DRSRPYPVPK DINTLIRSKV MPQDHLNYSI TWYSLSAAVT FMAYKRLKAK PVRR