ID   SURF1_CAEEL             Reviewed;         323 AA.
AC   Q9N5N8;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=SURF1-like protein;
GN   Name=sft-1; ORFNames=H06I04.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Probably involved in the biogenesis of the COX complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SURF1 family. {ECO:0000305}.
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DR   EMBL; FO081532; CCD72250.1; -; Genomic_DNA.
DR   RefSeq; NP_497657.1; NM_065256.3.
DR   AlphaFoldDB; Q9N5N8; -.
DR   STRING; 6239.H06I04.2; -.
DR   EPD; Q9N5N8; -.
DR   PaxDb; Q9N5N8; -.
DR   PeptideAtlas; Q9N5N8; -.
DR   EnsemblMetazoa; H06I04.2a.1; H06I04.2a.1; WBGene00004787.
DR   GeneID; 175415; -.
DR   KEGG; cel:CELE_H06I04.2; -.
DR   UCSC; H06I04.2; c. elegans.
DR   CTD; 175415; -.
DR   WormBase; H06I04.2a; CE23794; WBGene00004787; sft-1.
DR   eggNOG; KOG1563; Eukaryota.
DR   GeneTree; ENSGT00530000064194; -.
DR   HOGENOM; CLU_047737_4_0_1; -.
DR   InParanoid; Q9N5N8; -.
DR   OMA; WYSRDVA; -.
DR   OrthoDB; 923657at2759; -.
DR   PhylomeDB; Q9N5N8; -.
DR   PRO; PR:Q9N5N8; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00004787; Expressed in germ line (C elegans) and 4 other tissues.
DR   ExpressionAtlas; Q9N5N8; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IBA:GO_Central.
DR   CDD; cd06662; SURF1; 1.
DR   InterPro; IPR002994; Surf1/Shy1.
DR   InterPro; IPR045214; Surf1/Surf4.
DR   PANTHER; PTHR23427; PTHR23427; 1.
DR   Pfam; PF02104; SURF1; 1.
DR   PROSITE; PS50895; SURF1; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..323
FT                   /note="SURF1-like protein"
FT                   /id="PRO_0000344499"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        299..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          57..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        57..75
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   323 AA;  36842 MW;  C72F0EDA1B1C480C CRC64;
     MPLPAAAFAR ILVVSRQRLF NTRIIHTSGS GYSITQCRFY KTTPCLTHKQ SQILDLDAPK
     SRENREKDGG KSKKSKKSIK WSTGSVLMLT IPVFAFSLGI WQTFRLKWKL DLIEHLKGRL
     NQTAQELPED LSCESLEPLE YCRVTVTGEF LHEKEFIISP RGRFDPGKKT SAAAGSMLSE
     NEMSSHGGHL ITPFRLKNSG KIILINRGWL PSFYFDPETR QKTNPRGTLT LPAIVRKTEK
     RPQFVGQNVP EQGVWYYRDL NQMAKHYGTE PVLLDAAYET TVPGGPIGGQ TNINVRNEHL
     NYLTTWFTLT LVTMLMWIHK FRK