ID   SURF1_CHICK             Reviewed;         309 AA.
AC   Q800L1;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Surfeit locus protein 1;
GN   Name=SURF1; Synonyms=SURF-1;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Liver;
RA   Maeda N., Toku S., Kenmochi N., Tanaka T.;
RT   "The gene cluster containing ribosomal protein L7a gene of the chicken.";
RL   Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in mitochondrial respiratory chain complex IV
CC       assembly. Probably involved in the biogenesis of the COX complex.
CC       {ECO:0000250|UniProtKB:Q15526}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SURF1 family. {ECO:0000305}.
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DR   EMBL; AB050009; BAC65170.1; -; Genomic_DNA.
DR   RefSeq; NP_001012671.1; NM_001012653.2.
DR   AlphaFoldDB; Q800L1; -.
DR   STRING; 9031.ENSGALP00000005047; -.
DR   PaxDb; Q800L1; -.
DR   Ensembl; ENSGALT00000050043; ENSGALP00000050296; ENSGALG00000033754.
DR   GeneID; 417157; -.
DR   KEGG; gga:417157; -.
DR   CTD; 6834; -.
DR   VEuPathDB; HostDB:geneid_417157; -.
DR   eggNOG; KOG1563; Eukaryota.
DR   GeneTree; ENSGT00530000064194; -.
DR   HOGENOM; CLU_047737_4_0_1; -.
DR   InParanoid; Q800L1; -.
DR   OMA; WYSRDVA; -.
DR   OrthoDB; 923657at2759; -.
DR   PhylomeDB; Q800L1; -.
DR   TreeFam; TF314684; -.
DR   Reactome; R-GGA-5628897; TP53 Regulates Metabolic Genes.
DR   Reactome; R-GGA-611105; Respiratory electron transport.
DR   Reactome; R-GGA-9707564; Cytoprotection by HMOX1.
DR   PRO; PR:Q800L1; -.
DR   Proteomes; UP000000539; Chromosome 17.
DR   Bgee; ENSGALG00000033754; Expressed in heart and 13 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:Ensembl.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; ISS:UniProtKB.
DR   CDD; cd06662; SURF1; 1.
DR   InterPro; IPR002994; Surf1/Shy1.
DR   InterPro; IPR045214; Surf1/Surf4.
DR   PANTHER; PTHR23427; PTHR23427; 1.
DR   Pfam; PF02104; SURF1; 1.
DR   PROSITE; PS50895; SURF1; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..309
FT                   /note="Surfeit locus protein 1"
FT                   /id="PRO_0000215655"
FT   TRANSMEM        71..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   309 AA;  35210 MW;  209EEE454793035A CRC64;
     MATWGLLLRA GPRLLRERRA RISHCLLRRT FFGFPRTKAG SAVTQQGDVC LRLCSPRSST
     TATSAAGEDA WLKWGLLLVP LTAFCLGTWQ IQRRKWKLDL IAQLASRLSS EPIPLTLDPM
     ELKELEYRPV KVRGHFDHSK ELYILPRSLV DPEREAREAG KLTSHAENGA NVITPFYCTE
     LGVTILVNRG FVPKKKLKPE TRLKGQIEEE IDLTGVVRLS EKRKPFVPEN NIEKNRWHYR
     DLEAMAKVTG AEPIFIDADF RSTVPGGPIG GQTRVSLRNE HMQYIVTWYG LCAATSFLWY
     RKFIQKIPL