ID   SURF1_TAKRU             Reviewed;         240 AA.
AC   O57593;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Surfeit locus protein 1;
DE   Flags: Fragment;
GN   Name=surf1; Synonyms=surf-1;
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9414319; DOI=10.1101/gr.7.12.1138;
RA   Armes N., Gilley J., Fried M.;
RT   "The comparative genomic structure and sequence of the surfeit gene
RT   homologs in the puffer fish Fugu rubripes and their association with CpG-
RT   rich islands.";
RL   Genome Res. 7:1138-1152(1997).
CC   -!- FUNCTION: May play a role in mitochondrial respiratory chain complex IV
CC       assembly. Probably involved in the biogenesis of the COX complex.
CC       {ECO:0000250|UniProtKB:Q15526}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SURF1 family. {ECO:0000305}.
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DR   EMBL; Y15171; CAA75445.1; -; Genomic_DNA.
DR   PIR; T52090; T52090.
DR   AlphaFoldDB; O57593; -.
DR   STRING; 31033.ENSTRUP00000047074; -.
DR   eggNOG; KOG1563; Eukaryota.
DR   HOGENOM; CLU_047737_4_2_1; -.
DR   InParanoid; O57593; -.
DR   OMA; WYSRDVA; -.
DR   TreeFam; TF314684; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; ISS:UniProtKB.
DR   CDD; cd06662; SURF1; 1.
DR   InterPro; IPR002994; Surf1/Shy1.
DR   InterPro; IPR045214; Surf1/Surf4.
DR   PANTHER; PTHR23427; PTHR23427; 1.
DR   Pfam; PF02104; SURF1; 1.
DR   PROSITE; PS50895; SURF1; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           <1..240
FT                   /note="Surfeit locus protein 1"
FT                   /id="PRO_0000215656"
FT   TRANSMEM        2..20
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        215..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
SQ   SEQUENCE   240 AA;  27366 MW;  B5F4297A36232973 CRC64;
     SFLKWFLLLI PATTFGLGTW QVKRRQWKME LIDGLTKLTT AEPIPLPIDP AELSSLEYRR
     VKMRGKYDHS KELYILPRSP VDPEKEAREA GRLSSSGETG ANVITPFHVT DLGITILVNR
     GYVPKKKIRP ETRMKGQVEG EMEVVGVVRL TETRKPFVPN NDVERNHWHY RDLEAMCQVT
     GAEPIFVDAD FSSTVPGGPI GGQTRVTLRN EHMQYIVTWY GLCAATSYMW FAKFIKKIKV