ID   SURF6_DICDI             Reviewed;         396 AA.
AC   Q54G38;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Surfeit locus protein 6 homolog;
GN   Name=surf6; ORFNames=DDB_G0290425;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Involved in a nucleolar function. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SURF6 family. {ECO:0000305}.
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DR   EMBL; AAFI02000163; EAL62228.1; -; Genomic_DNA.
DR   RefSeq; XP_635734.1; XM_630642.1.
DR   AlphaFoldDB; Q54G38; -.
DR   SMR; Q54G38; -.
DR   STRING; 44689.DDB0188884; -.
DR   PaxDb; Q54G38; -.
DR   EnsemblProtists; EAL62228; EAL62228; DDB_G0290425.
DR   GeneID; 8627652; -.
DR   KEGG; ddi:DDB_G0290425; -.
DR   dictyBase; DDB_G0290425; -.
DR   eggNOG; KOG2885; Eukaryota.
DR   HOGENOM; CLU_697238_0_0_1; -.
DR   InParanoid; Q54G38; -.
DR   OMA; MSSMFNI; -.
DR   PRO; PR:Q54G38; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IBA:GO_Central.
DR   InterPro; IPR029190; Rrp14/SURF6_C.
DR   InterPro; IPR007019; SURF6.
DR   PANTHER; PTHR14369; PTHR14369; 1.
DR   Pfam; PF04935; SURF6; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..396
FT                   /note="Surfeit locus protein 6 homolog"
FT                   /id="PRO_0000356273"
FT   REGION          26..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          341..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..89
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        108..132
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        133..153
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        154..172
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..223
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        358..372
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   396 AA;  44976 MW;  90826903C7A8314B CRC64;
     MSDLKSRLKE TSNWMSSMFN IIKDPTSESA SFSNRVNSVA PPPRRSSSSS SISFSELTNS
     NENKTTTTTT TTTTSTTATT SQPPQKSPVE QNKEELKKLL QQQLAEMKLK RQGKNSNIND
     SNNSNNNNNN TDKNKNDNKK EIIKNKKIKE EEESEGEEVE EEEEEESDIS DSEDNNSSNN
     NGSLNGDYDD YGDEISESGS EMDLINNKNL NKEKRKKQEE DLQFSTFDFS SGKAMPTYLM
     NKGRKTSKKE LLEKAEEKER ILANSKRNGT NKELADTIRW STAFDKVQGI KVKDDPALLR
     KSIKKVEKTK LKSAREWVQR KKEKDEKLKV RIAKREANIK AKIEEKKERR MGIKKKKTNN
     NNNKSGGGGG NSHASRQRAG FEGKKKFHFN PKKLIN