ABITM_DROME
ID ABITM_DROME Reviewed; 214 AA.
AC Q9VFR1;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Protein Abitram {ECO:0000305};
DE AltName: Full=Actin-binding transcription modulator;
GN Name=abitram; ORFNames=CG9288;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley; TISSUE=Embryo;
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC -!- FUNCTION: May regulate actin polymerization.
CC {ECO:0000250|UniProtKB:Q80ZQ9}.
CC -!- SIMILARITY: Belongs to the ABITRAM family. {ECO:0000305}.
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DR EMBL; AE014297; AAF54989.1; -; Genomic_DNA.
DR EMBL; AY069582; AAL39727.1; -; mRNA.
DR RefSeq; NP_650316.1; NM_142059.3.
DR AlphaFoldDB; Q9VFR1; -.
DR BioGRID; 66768; 5.
DR IntAct; Q9VFR1; 1.
DR STRING; 7227.FBpp0082297; -.
DR PaxDb; Q9VFR1; -.
DR EnsemblMetazoa; FBtr0082829; FBpp0082297; FBgn0260464.
DR GeneID; 41689; -.
DR KEGG; dme:Dmel_CG9288; -.
DR UCSC; CG9288-RA; d. melanogaster.
DR FlyBase; FBgn0260464; CG9288.
DR VEuPathDB; VectorBase:FBgn0260464; -.
DR eggNOG; KOG3266; Eukaryota.
DR GeneTree; ENSGT00450000040303; -.
DR HOGENOM; CLU_107323_1_0_1; -.
DR InParanoid; Q9VFR1; -.
DR OMA; RYYYFKG; -.
DR PhylomeDB; Q9VFR1; -.
DR BioGRID-ORCS; 41689; 1 hit in 1 CRISPR screen.
DR GenomeRNAi; 41689; -.
DR PRO; PR:Q9VFR1; -.
DR Proteomes; UP000000803; Chromosome 3R.
DR Bgee; FBgn0260464; Expressed in Malpighian tubule and 13 other tissues.
DR Genevisible; Q9VFR1; DM.
DR GO; GO:0030425; C:dendrite; IBA:GO_Central.
DR GO; GO:0032433; C:filopodium tip; IBA:GO_Central.
DR GO; GO:0030027; C:lamellipodium; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0003785; F:actin monomer binding; IBA:GO_Central.
DR GO; GO:0048813; P:dendrite morphogenesis; IBA:GO_Central.
DR GO; GO:0030833; P:regulation of actin filament polymerization; IBA:GO_Central.
DR GO; GO:0051489; P:regulation of filopodium assembly; IBA:GO_Central.
DR InterPro; IPR039169; Abitram.
DR InterPro; IPR033753; GCV_H/Fam206.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR13651; PTHR13651; 1.
DR Pfam; PF01597; GCV_H; 1.
DR SUPFAM; SSF51230; SSF51230; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..214
FT /note="Protein Abitram"
FT /id="PRO_0000291935"
FT REGION 189..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 214 AA; 23831 MW; 2ED5F5EDDF20E6AC CRC64;
MSVQADDPLE PFYFEHEEQE ICGKLVAPIT DSFQEDYPSV VDRFFTRYYY FKGDVPYQVL
YHSNRICLIC LAPEHPALAQ GISSVNFDIG NVDRSQNVVK GKGKKGGMIL QAESTLALLT
TANGGTYKVP SCIRGKLVEV NTAIVEEPKL LEQLPEGAGY FAILLPKIEN CDAIKASLLT
QEQYEERLKS KNEGLPQIES TGDHAQNKNK EIQA
