ID   SUS_VICFA               Reviewed;         806 AA.
AC   P31926;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Sucrose synthase;
DE            EC=2.4.1.13;
DE   AltName: Full=Sucrose-UDP glucosyltransferase;
GN   Name=SUCS;
OS   Vicia faba (Broad bean) (Faba vulgaris).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Fabeae; Vicia.
OX   NCBI_TaxID=3906;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Fribo;
RX   PubMed=7764025; DOI=10.1007/bf00195698;
RA   Heim U., Weber H., Baumlein H., Wobus U.;
RT   "A sucrose-synthase gene of Vicia faba L.: expression pattern in developing
RT   seeds in relation to starch synthesis and metabolic regulation.";
RL   Planta 191:394-401(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Kleine Thueringer; TISSUE=Root nodule;
RX   PubMed=8400379; DOI=10.1094/mpmi-6-507;
RA   Kuster H., Fruhling M., Perlick A.M., Puehler A.;
RT   "The sucrose synthase gene is predominantly expressed in the root nodule
RT   tissue of Vicia faba.";
RL   Mol. Plant Microbe Interact. 6:507-514(1993).
CC   -!- FUNCTION: Sucrose-cleaving enzyme that provides UDP-glucose and
CC       fructose for various metabolic pathways.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an NDP-alpha-D-glucose + D-fructose = a ribonucleoside 5'-
CC         diphosphate + H(+) + sucrose; Xref=Rhea:RHEA:16241,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17992, ChEBI:CHEBI:37721,
CC         ChEBI:CHEBI:57930, ChEBI:CHEBI:76533; EC=2.4.1.13;
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family. Plant sucrose
CC       synthase subfamily. {ECO:0000305}.
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DR   EMBL; X69773; CAA49428.1; -; mRNA.
DR   EMBL; M97551; AAC37346.1; -; mRNA.
DR   PIR; S31479; S31479.
DR   AlphaFoldDB; P31926; -.
DR   SMR; P31926; -.
DR   BRENDA; 2.4.1.13; 986.
DR   GO; GO:0016157; F:sucrose synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005985; P:sucrose metabolic process; IEA:InterPro.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR000368; Sucrose_synth.
DR   InterPro; IPR012820; Sucrose_synthase_pln/cyn.
DR   PANTHER; PTHR45839; PTHR45839; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   Pfam; PF00862; Sucrose_synth; 1.
DR   TIGRFAMs; TIGR02470; sucr_synth; 1.
PE   2: Evidence at transcript level;
KW   Glycosyltransferase; Transferase.
FT   CHAIN           1..806
FT                   /note="Sucrose synthase"
FT                   /id="PRO_0000204666"
FT   REGION          275..752
FT                   /note="GT-B glycosyltransferase"
FT                   /evidence="ECO:0000250|UniProtKB:P49040"
SQ   SEQUENCE   806 AA;  92521 MW;  A54B004C0732F306 CRC64;
     MATERLTRVH SLRERLDETL TANRNEILAL LSRIEAKGKG ILQHHQVIAE FEEIPEENRQ
     KLTDGAFGEV LRSTQEAIVL PPWVALAVRP RPGVWEYLRV NVHALVVENL QPAEFLKFKE
     ELVDGSANGN FVLELDFEPF TASFPRPTLN KSIGNGVQFL NRHLSAKLFH DKESLHPLLE
     FLRLHSYKGK TLMLNDRIQN PDSLQHVLRK AEEYLSTVDP ETPYSEFEHR FQEIGLERGW
     GDSAERVLES IQLLLDLLEA PDPCTLETFL DRIPMVFNVV ILSPHGYFAQ DDVLGYPDTG
     GQVVYILDQV RALESEMLNR IKKQGLDIVP RILIITRLLP DAVGTTCGQR LEKVYGTEHC
     HILRVPFRDQ KGIVRKWISR FEVWPYLETY TEDVAHELAK ELQGKPDLIV GNYSDGNIVA
     SLLAHKLGVT QCTIAHALEK TKYPESDIYW KKFEEKYHFS CQFTADLFAM NHTDFIITST
     FQEIAGSKDT VGQYESHTAF TLPGLYRVVH GIDVFDPKFN IVSPGADQTI YFPYTETSRR
     LTSFYPEIEE LLYSTVENEE HICVLKDRSK PIIFTMARLD RVKNITGLVE WYGKNAKLRE
     LVNLVVVAGD RRKESKDLEE KAEMKKMYEL IETYKLNGQF RWISSQMNRV RNGELYRVIC
     DTKGAFVQPA VYEAFGLTVV EAMATGLPTF ATLNGGPAEI IVHGKSGFHI DPYHGDRAAD
     LLVEFFEKVK ADPSHWDKIS LGGLQRIEEK YTWQIYSQRL LTLTGVYGFW KHVSNLDRLE
     SRRYLEMFYA LKYRKLAESV PLAVEE