ID   SUT1_STYHA              Reviewed;         667 AA.
AC   P53391;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=High affinity sulfate transporter 1;
GN   Name=ST1;
OS   Stylosanthes hamata (Caribbean stylo).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   dalbergioids sensu lato; Dalbergieae; Pterocarpus clade; Stylosanthes.
OX   NCBI_TaxID=37660;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Verano; TISSUE=Root;
RX   PubMed=7568135; DOI=10.1073/pnas.92.20.9373;
RA   Smith F.W., Ealing P.M., Hawkesford M.J., Clarkson D.T.;
RT   "Plant members of a family of sulfate transporters reveal functional
RT   subtypes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:9373-9377(1995).
CC   -!- FUNCTION: High-affinity H(+)/sulfate cotransporter that mediates the
CC       uptake of sulfate by plant roots from low concentrations of sulfate in
CC       the soil solution.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC       {ECO:0000305}.
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DR   EMBL; X82255; CAA57710.1; -; mRNA.
DR   PIR; S51763; S51763.
DR   AlphaFoldDB; P53391; -.
DR   SMR; P53391; -.
DR   TCDB; 2.A.53.1.3; the sulfate permease (sulp) family.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.750.24; -; 1.
DR   InterPro; IPR018045; S04_transporter_CS.
DR   InterPro; IPR011547; SLC26A/SulP_dom.
DR   InterPro; IPR001902; SLC26A/SulP_fam.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   PANTHER; PTHR11814; PTHR11814; 1.
DR   Pfam; PF01740; STAS; 1.
DR   Pfam; PF00916; Sulfate_transp; 1.
DR   SUPFAM; SSF52091; SSF52091; 1.
DR   TIGRFAMs; TIGR00815; sulP; 1.
DR   PROSITE; PS01130; SLC26A; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..667
FT                   /note="High affinity sulfate transporter 1"
FT                   /id="PRO_0000080189"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        350..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        452..472
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        486..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          537..660
FT                   /note="STAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
FT   REGION          16..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   667 AA;  73173 MW;  1A7AD47FDEB4DA7E CRC64;
     MSQRVSDQVM ADVIAETRSN SSSHRHGGGG GGDDTTSLPY MHKVGTPPKQ TLFQEIKHSF
     NETFFPDKPF GKFKDQSGFR KLELGLQYIF PILEWGRHYD LKKFRGDFIA GLTIASLCIP
     QDLAYAKLAN LDPWYGLYSS FVAPLVYAFM GTSRDIAIGP VAVVSLLLGT LLSNEISNTK
     SHDYLRLAFT ATFFAGVTQM LLGVCRLGFL IDFLSHAAIV GFMAGAAITI GLQQLKGLLG
     ISNNNFTKKT DIISVMRSVW THVHHGWNWE TILIGLSFLI FLLITKYIAK KNKKLFWVSA
     ISPMISVIVS TFFVYITRAD KRGVSIVKHI KSGVNPSSAN EIFFHGKYLG AGVRVGVVAG
     LVALTEAIAI GRTFAAMKDY ALDGNKEMVA MGTMNIVGSL SSCYVTTGSF SRSAVNYMAG
     CKTAVSNIVM SIVVLLTLLV ITPLFKYTPN AVLASIIIAA VVNLVNIEAM VLLWKIDKFD
     FVACMGAFFG VIFKSVEIGL LIAVAISFAK ILLQVTRPRT AVLGKLPGTS VYRNIQQYPK
     AAQIPGMLII RVDSAIYFSN SNYIKERILR WLIDEGAQRT ESELPEIQHL ITEMSPVPDI
     DTSGIHAFEE LYKTLQKREV QLILANPGPV VIEKLHASKL TELIGEDKIF LTVADAVATY
     GPKTAAF