SUT31_ARATH
ID SUT31_ARATH Reviewed; 658 AA.
AC Q9SV13; O23250; O64435; O65025;
DT 26-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Sulfate transporter 3.1;
DE AltName: Full=AST12;
DE AltName: Full=AtST1;
GN Name=SULTR3;1; Synonyms=ST1; OrderedLocusNames=At3g51895;
GN ORFNames=ATEM1.15, F4F15.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Landsberg erecta; TISSUE=Aerial part;
RA Yamaguchi Y., Nakamura T., Harada E., Koizumi N., Sano H.;
RT "Isolation and characterization of a cDNA encoding a sulfate transporter
RT from Arabidopsis thaliana.";
RL (er) Plant Gene Register PGR97-051(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Columbia;
RA Takahashi H., Sasakura N., Kimura A., Watanabe A., Saito K.;
RT "Identification of two leaf-specific sulfate transporters in Arabidopsis
RT thaliana.";
RL (er) Plant Gene Register PGR99-154(1999).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10645728; DOI=10.1023/a:1006395324818;
RA Comella P., Wu H.-J., Laudie M., Berger C., Cooke R., Delseny M.,
RA Grellet F.;
RT "Fine sequence analysis of 60 kb around the Arabidopsis thaliana AtEm1
RT locus on chromosome III.";
RL Plant Mol. Biol. 41:687-700(1999).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: H(+)/sulfate cotransporter that may play a role in the
CC regulation of sulfate assimilation.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed only in leaves.
CC -!- INDUCTION: By nitrogen starvation, but not by sulfate starvation.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC14417.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=BAA25175.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; D89631; BAA21657.1; -; mRNA.
DR EMBL; AB012048; BAA25175.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AF049236; AAC14417.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL049711; CAB41310.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78860.1; -; Genomic_DNA.
DR EMBL; AY099873; AAM20724.1; -; mRNA.
DR PIR; T48901; T48901.
DR PIR; T48902; T48902.
DR PIR; T49069; T49069.
DR PIR; T51161; T51161.
DR RefSeq; NP_190758.2; NM_115049.5.
DR AlphaFoldDB; Q9SV13; -.
DR SMR; Q9SV13; -.
DR BioGRID; 9671; 2.
DR STRING; 3702.AT3G51895.1; -.
DR PaxDb; Q9SV13; -.
DR PRIDE; Q9SV13; -.
DR ProteomicsDB; 226756; -.
DR EnsemblPlants; AT3G51895.1; AT3G51895.1; AT3G51895.
DR GeneID; 824353; -.
DR Gramene; AT3G51895.1; AT3G51895.1; AT3G51895.
DR KEGG; ath:AT3G51895; -.
DR Araport; AT3G51895; -.
DR TAIR; locus:3437527; AT3G51895.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_13_2_1; -.
DR InParanoid; Q9SV13; -.
DR OMA; VTNKFPI; -.
DR PhylomeDB; Q9SV13; -.
DR PRO; PR:Q9SV13; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SV13; baseline and differential.
DR Genevisible; Q9SV13; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0015301; F:anion:anion antiporter activity; IBA:GO_Central.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; IMP:TAIR.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008272; P:sulfate transport; IMP:TAIR.
DR Gene3D; 3.30.750.24; -; 1.
DR InterPro; IPR018045; S04_transporter_CS.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR InterPro; IPR030311; Sul_transpt_3.1.
DR PANTHER; PTHR11814; PTHR11814; 1.
DR PANTHER; PTHR11814:SF224; PTHR11814:SF224; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SSF52091; 1.
DR TIGRFAMs; TIGR00815; sulP; 1.
DR PROSITE; PS01130; SLC26A; 1.
DR PROSITE; PS50801; STAS; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Stress response; Sulfate transport; Symport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..658
FT /note="Sulfate transporter 3.1"
FT /id="PRO_0000080177"
FT TOPO_DOM 1..85
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 107..108
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 130..133
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 155..163
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 185
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 207..245
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 246..266
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 267..271
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 293..332
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 354..363
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 364..384
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 385..398
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 420..425
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 426..446
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 447..464
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 465..485
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 486..658
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 513..637
FT /note="STAS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
FT CONFLICT 208
FT /note="V -> L (in Ref. 3; AAC14417)"
FT /evidence="ECO:0000305"
FT CONFLICT 344
FT /note="V -> I (in Ref. 1; BAA21657)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 658 AA; 72748 MW; ED1860A3467FB577 CRC64;
MGTEDYTFPQ GAEELHRRHH TVEAPQPQPF LKSLQYSVKE TLFPDDPFRQ FKNQNASRKF
VLGLKYFLPI FEWAPRYNLK FFKSDLIAGI TIASLAIPQG ISYAKLANLP PILGLYSSFV
PPLVYAVLGS SRDLAVGTVA VASLLTGAML SKEVDAEKDP KLYLHLAFTA TFFAGVLEAS
LGIFRLGFIV DFLSHATIVG FMGGAATVVS LQQLKGIFGL KHFTDSTDVI SVMRSVFSQT
HEWRWESGVL GCGFLFFLLS TRYFSIKKPK FFWVAAMAPL TSVILGSLLV YFTHAERHGV
QVIGDLKKGL NPLSGSDLIF TSPYMSTAVK TGLITGIIAL AEGVAVGRSF AMFKNYNIDG
NKEMIAFGMM NIVGSFTSCY LTTGPFSRSA VNYNAGCKTA MSNIVMAIAV MFTLLFLTPL
FHYTPLVVLS AIIISAMLGL IDYQAAIHLW KVDKFDFLVC MSAYVGVVFG SVEIGLVVAV
AISIARLLLF VSRPKTAVKG NIPNSMIYRN TEQYPSSRTV PGILILEIDA PIYFANASYL
RERIIRWIDE EEERVKQSGE SSLQYIILDM SAVGNIDTSG ISMMVEIKKV IDRRALKLVL
SNPKGEVVKK LTRSKFIGDH LGKEWMFLTV GEAVEACSYM LHTFKTEPAS KNEPWNNV
