SUT4_ORYSJ
ID SUT4_ORYSJ Reviewed; 595 AA.
AC Q6YK44; Q84KR4;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Sucrose transport protein SUT4;
DE AltName: Full=Sucrose permease 4;
DE AltName: Full=Sucrose transporter 4;
DE Short=OsSUT4;
DE AltName: Full=Sucrose-proton symporter 4;
GN Name=SUT4; Synonyms=SUT2; OrderedLocusNames=Os02g0827200, LOC_Os02g58080;
GN ORFNames=OsJ_08963;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Nipponbare; TISSUE=Panicle;
RX PubMed=12668768; DOI=10.1093/pcp/pcg030;
RA Aoki N., Hirose T., Scofield G.N., Whitfeld P.R., Furbank R.T.;
RT "The sucrose transporter gene family in rice.";
RL Plant Cell Physiol. 44:223-232(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Zhonghua 15; TISSUE=Endosperm;
RA Wang Y.D., Wang X.S.;
RT "Cloning and functional clarification of a sucrose transporter gene in the
RT developing endosperm and embryo for rice (Oryza sativa).";
RL Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Responsible for the transport of sucrose into the cell, with
CC the concomitant uptake of protons (symport system). May also transport
CC other glucosides (By similarity). {ECO:0000250}.
CC -!- PATHWAY: Glycan biosynthesis; sucrose metabolism.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Widely expressed. Highest expression in sink leaves
CC and lowest in germinating seeds. {ECO:0000269|PubMed:12668768}.
CC -!- DEVELOPMENTAL STAGE: Expressed in developing caryopses from 1 to 7 days
CC after flowering (DAF) and then declines to nearly undetectable levels
CC by 15 DAF. {ECO:0000269|PubMed:12668768}.
CC -!- SIMILARITY: Belongs to the glycoside-pentoside-hexuronide (GPH) cation
CC symporter transporter (TC 2.A.2.4) family. {ECO:0000305}.
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DR EMBL; AB091673; BAC67164.1; -; mRNA.
DR EMBL; AY137242; AAN15219.1; -; mRNA.
DR EMBL; AP008208; BAF10505.1; -; Genomic_DNA.
DR EMBL; AP014958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000139; EEE58094.1; -; Genomic_DNA.
DR RefSeq; XP_015625556.1; XM_015770070.1.
DR AlphaFoldDB; Q6YK44; -.
DR STRING; 4530.OS02T0827200-01; -.
DR PaxDb; Q6YK44; -.
DR PRIDE; Q6YK44; -.
DR GeneID; 4331221; -.
DR KEGG; osa:4331221; -.
DR eggNOG; KOG0637; Eukaryota.
DR HOGENOM; CLU_065261_0_0_1; -.
DR InParanoid; Q6YK44; -.
DR OrthoDB; 1230185at2759; -.
DR UniPathway; UPA00238; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q6YK44; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008506; F:sucrose:proton symporter activity; IBA:GO_Central.
DR GO; GO:0005985; P:sucrose metabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; Membrane; Reference proteome; Sugar transport;
KW Symport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..595
FT /note="Sucrose transport protein SUT4"
FT /id="PRO_0000398193"
FT TOPO_DOM 1..61
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 83..97
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 119..130
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 152..173
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 195..213
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 235..256
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 278..365
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 387..417
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 418..438
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 439..447
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 448..468
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 469..491
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 492..512
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 513..525
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 526..546
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 547..556
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 557..577
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 578..595
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 29..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 403
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 484
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 190
FT /note="N -> H (in Ref. 1; BAC67164)"
FT /evidence="ECO:0000305"
FT CONFLICT 430
FT /note="I -> F (in Ref. 1; BAC67164)"
FT /evidence="ECO:0000305"
FT CONFLICT 507
FT /note="S -> G (in Ref. 1; BAC67164)"
FT /evidence="ECO:0000305"
FT CONFLICT 522
FT /note="G -> S (in Ref. 1; BAC67164)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 595 AA; 63484 MW; 3D232D6ABA7A7935 CRC64;
MDSAAGGGGL TAIRLPYRHL RDAEMELVSL NGGTPRGGSP KDPDATHQQG PPAARTTTTR
KLVLACMVAA GVQFGWALQL SLLTPYIQTL GIDHAMASFI WLCGPITGFV VQPCVGVWSD
KCRSKYGRRR PFILAGCLMI CFAVTLIGFS ADLGYILGDT TEHCSTYKGS RFRAAIIFVL
GFWMLDLANN TVQGPARALL ADLSGPDQCN SANAIFCTWM AVGNVLGFSS GASGNWHKWF
PFLMTRACCE ACSNLKAAFL VAVVFLLFCM SVTLYFAEEI PLEPTDAQRL SDSAPLLNGS
RDDNNASNEP RNGALPNGHT DGSNVPANSN AEDSNSNREN VEVFNDGPGA VLVNILTSMR
HLPPGMYSVL LVMALTWLSW FPFFLFDTDW MGREVYHGDP NGNLSERKAY DNGVREGAFG
LLLNSVVLGI GSFLVDPLCR LMGARLVWAI SNFTVFICML ATAILSWISF DLYSSKLHHI
IGANKTVKNS ALIVFSLLGL PLSITYSVPF SVTAELTAGT GGGQGLATGV LNLAIVVPQI
VVSLGAGPWD ALFGGGNVPA FALASVFSLG AGVLAVLKLP KLPNSYRSAG FHGFG
