ID   SUT_SPIOL               Reviewed;         525 AA.
AC   Q03411;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Sucrose transport protein;
DE   AltName: Full=Sucrose permease;
DE   AltName: Full=Sucrose-proton symporter;
OS   Spinacia oleracea (Spinach).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   Caryophyllales; Chenopodiaceae; Chenopodioideae; Anserineae; Spinacia.
OX   NCBI_TaxID=3562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Leaf;
RX   PubMed=1464305; DOI=10.1002/j.1460-2075.1992.tb05575.x;
RA   Riesmeier J.W., Willmitzer L., Frommer W.B.;
RT   "Isolation and characterization of a sucrose carrier cDNA from spinach by
RT   functional expression in yeast.";
RL   EMBO J. 11:4705-4713(1992).
CC   -!- FUNCTION: Responsible for the transport of sucrose into the cell, with
CC       the concomitant uptake of protons (symport system). Can also transport
CC       maltose at a lesser rate.
CC   -!- PATHWAY: Glycan biosynthesis; sucrose metabolism.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the glycoside-pentoside-hexuronide (GPH) cation
CC       symporter transporter (TC 2.A.2.4) family. {ECO:0000305}.
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DR   EMBL; X67125; CAA47604.1; -; mRNA.
DR   PIR; S28052; S28052.
DR   AlphaFoldDB; Q03411; -.
DR   OrthoDB; 1230185at2759; -.
DR   UniPathway; UPA00238; -.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0008515; F:sucrose transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0005985; P:sucrose metabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR005989; Suc_symporter_pln.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR01301; GPH_sucrose; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Sugar transport; Symport; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..525
FT                   /note="Sucrose transport protein"
FT                   /id="PRO_0000122531"
FT   TOPO_DOM        1..37
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..165
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        184..204
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        230..250
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        295..315
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        338..358
FT                   /note="Helical; Name=8"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        373..393
FT                   /note="Helical; Name=9"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        422..442
FT                   /note="Helical; Name=10"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        455..475
FT                   /note="Helical; Name=11"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        488..508
FT                   /note="Helical; Name=12"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        509..525
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   525 AA;  54992 MW;  018347A4D2CC1CC6 CRC64;
     MAGRNIKNGE NNKIAGSSLH LEKNPTTPPE AEATLKKLGL VASVAAGVQF GWALQLSLLT
     PYVQLLGIPH TWAAYIWLCG PISGMIVQPL VGYYSDRCTS RFGRRRPFIA AGAALVAVAV
     GLIGFAADIG AASGDPTGNV AKPRAIAVFV VGFWILDVAN NTLQGPCRAL LADMAAGSQT
     KTRYANAFFS FFMALGNIGG YAAGSYSRLY TVFPFTKTAA CDVYCANLKS CFFISITLLI
     VLTILALSVV KERQITIDEI QEEEDLKNRN NSSGCARLPF FGQLIGALKD LPKPMLILLL
     VTALNWIAWF PFLLFDTDWM GKEVYGGTVG EGKLYDQGVH AGALGLMINS VVLGVMSLSI
     EGLARMVGGA KRLWGIVNII LAVCLAMTVL VTKSAEHFRD SHHIMGSAVP PPPPAGVKGG
     ALAIFAVLGI PLAITFSIPF ALASIFSASS GSGQGLSLGV LNLAIVVPQM FVSVTSGPWD
     AMFGGGNLPA FVVGAVAATA SAVLSFTLLP SPPPEAKIGG SMGGH