ID   SVBP_BOVIN              Reviewed;          66 AA.
AC   Q32LJ0;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Small vasohibin-binding protein {ECO:0000250|UniProtKB:Q8N300};
DE   AltName: Full=Coiled coil domain-containing protein 23 {ECO:0000250|UniProtKB:Q8N300};
GN   Name=SVBP {ECO:0000250|UniProtKB:Q8N300};
GN   Synonyms=CCDC23 {ECO:0000250|UniProtKB:Q8N300};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Enhances the tyrosine carboxypeptidase activity of VASH1 and
CC       VASH2, thereby promoting the removal of the C-terminal tyrosine residue
CC       of alpha-tubulin. Also required to enhance the solubility and secretion
CC       of VASH1 and VASH2. Plays a role in axon and excitatory synapse
CC       formation (By similarity). {ECO:0000250|UniProtKB:Q4KLG3,
CC       ECO:0000250|UniProtKB:Q8N300}.
CC   -!- SUBUNIT: Interacts with VASH1 and VASH2.
CC       {ECO:0000250|UniProtKB:Q8N300}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q99LQ4}.
CC       Secreted {ECO:0000250|UniProtKB:Q99LQ4}. Cytoplasm, cytoskeleton
CC       {ECO:0000250|UniProtKB:Q8N300}. Note=Detected both intracellularly and
CC       extracellularly. Within cells, localizes mainly to the apical part of
CC       the cell. {ECO:0000250|UniProtKB:Q99LQ4}.
CC   -!- SIMILARITY: Belongs to the SVBP family. {ECO:0000305}.
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DR   EMBL; BC109552; AAI09553.1; -; mRNA.
DR   RefSeq; NP_001035665.1; NM_001040575.1.
DR   RefSeq; XP_005204903.1; XM_005204846.3.
DR   RefSeq; XP_005204904.1; XM_005204847.1.
DR   RefSeq; XP_005204905.1; XM_005204848.2.
DR   RefSeq; XP_005204906.1; XM_005204849.3.
DR   RefSeq; XP_005204907.1; XM_005204850.3.
DR   AlphaFoldDB; Q32LJ0; -.
DR   SMR; Q32LJ0; -.
DR   STRING; 9913.ENSBTAP00000040566; -.
DR   PaxDb; Q32LJ0; -.
DR   Ensembl; ENSBTAT00000042962; ENSBTAP00000040566; ENSBTAG00000017388.
DR   GeneID; 614073; -.
DR   KEGG; bta:614073; -.
DR   CTD; 374969; -.
DR   VEuPathDB; HostDB:ENSBTAG00000017388; -.
DR   VGNC; VGNC:35497; SVBP.
DR   eggNOG; ENOG502S99I; Eukaryota.
DR   GeneTree; ENSGT00390000006113; -.
DR   HOGENOM; CLU_2830589_0_0_1; -.
DR   InParanoid; Q32LJ0; -.
DR   OMA; TFCKQMQ; -.
DR   OrthoDB; 1606567at2759; -.
DR   TreeFam; TF344015; -.
DR   Proteomes; UP000009136; Chromosome 3.
DR   Bgee; ENSBTAG00000017388; Expressed in semen and 104 other tissues.
DR   GO; GO:0045177; C:apical part of cell; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0061564; P:axon development; ISS:UniProtKB.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IBA:GO_Central.
DR   GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR   GO; GO:0006508; P:proteolysis; ISS:UniProtKB.
DR   GO; GO:1905048; P:regulation of metallopeptidase activity; ISS:UniProtKB.
DR   InterPro; IPR031378; SVBP.
DR   PANTHER; PTHR34762; PTHR34762; 1.
DR   Pfam; PF15674; CCDC23; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome; Secreted.
FT   CHAIN           1..66
FT                   /note="Small vasohibin-binding protein"
FT                   /id="PRO_0000233662"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          5..52
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   66 AA;  7828 MW;  A47B2B6DB9816CD1 CRC64;
     MDPPARKEKP KVKEPVSRIE KAKQKSAQQE LKQRQRAEIY ALNRVMTELE QQQFDEFCKQ
     MQPPGE