ID   SVF1_KLULA              Reviewed;         403 AA.
AC   Q6CQY2;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Survival factor 1;
GN   Name=SVF1; OrderedLocusNames=KLLA0D13332g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in the response to oxidative stress.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SVF1 family. {ECO:0000305}.
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DR   EMBL; CR382124; CAH00753.1; -; Genomic_DNA.
DR   RefSeq; XP_453657.1; XM_453657.1.
DR   AlphaFoldDB; Q6CQY2; -.
DR   STRING; 28985.XP_453657.1; -.
DR   EnsemblFungi; CAH00753; CAH00753; KLLA0_D13332g.
DR   GeneID; 2893433; -.
DR   KEGG; kla:KLLA0_D13332g; -.
DR   eggNOG; ENOG502QQY3; Eukaryota.
DR   HOGENOM; CLU_030205_3_1_1; -.
DR   InParanoid; Q6CQY2; -.
DR   OMA; AFWPRCV; -.
DR   Proteomes; UP000000598; Chromosome D.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:EnsemblFungi.
DR   InterPro; IPR033394; Svf1-like_C.
DR   InterPro; IPR013931; Svf1-like_N.
DR   Pfam; PF08622; Svf1; 1.
DR   Pfam; PF17187; Svf1_C; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..403
FT                   /note="Survival factor 1"
FT                   /id="PRO_0000072332"
SQ   SEQUENCE   403 AA;  45864 MW;  709B98DBEC4E9F11 CRC64;
     MLKWIQGGIS AVTGIAEPEY GQEYIHPCTE RVKGKQPFHV TSTKDFEWRN PDYTNVETST
     FYFTDLETGY TGFAQVIHSN IIGLHTTAQF TFRIYHKENT DDQIWTSVKL ENFRIEGTNF
     YADNLSIVMN EEGTEVQFKS TVDENVEVDF TIRRAVDGVK VGEDPSTYYG DDVTQPWGSM
     RHVFWPRNHI SGKIAAKNEE TNVKIDLQFS EEKKHYSMFV FAMQGMKPHH AAKSWTFLNF
     QSEDYTAVLM EFTTPKSYAN TTVNIGIVCD TKNILSVTVD NDAEYIDPEV DSVGWPVPKE
     ISVSFNGINA DIKDDDVESA DPFNTIVKGK LDNLVERVDV MAEIPTFVKN IVSGVAGTKP
     YIYQFFDDFE LTIKDQESKG FGWCEITFIS ESSEVEESAY DEN