ID   SVOPL_DANRE             Reviewed;         506 AA.
AC   Q1LVS8; Q5U3R1;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Putative transporter SVOPL;
DE   AltName: Full=SVOP-like protein;
GN   Name=svopl; ORFNames=si:dkeyp-27e10.2, zgc:101741;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 24-506.
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH85429.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BX649444; CAK11366.1; -; Genomic_DNA.
DR   EMBL; BC085429; AAH85429.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001007408.2; NM_001007407.2.
DR   RefSeq; NP_001038694.1; NM_001045229.1.
DR   RefSeq; XP_017210498.1; XM_017355009.1.
DR   AlphaFoldDB; Q1LVS8; -.
DR   SMR; Q1LVS8; -.
DR   STRING; 7955.ENSDARP00000075190; -.
DR   PaxDb; Q1LVS8; -.
DR   Ensembl; ENSDART00000080744; ENSDARP00000075190; ENSDARG00000057983.
DR   Ensembl; ENSDART00000150664; ENSDARP00000125241; ENSDARG00000057983.
DR   GeneID; 492766; -.
DR   KEGG; dre:492766; -.
DR   CTD; 136306; -.
DR   ZFIN; ZDB-GENE-041114-109; svopl.
DR   eggNOG; KOG0253; Eukaryota.
DR   GeneTree; ENSGT00940000158632; -.
DR   HOGENOM; CLU_001265_46_0_1; -.
DR   InParanoid; Q1LVS8; -.
DR   OMA; QIWIIWL; -.
DR   OrthoDB; 1430447at2759; -.
DR   PhylomeDB; Q1LVS8; -.
DR   TreeFam; TF313465; -.
DR   PRO; PR:Q1LVS8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 4.
DR   Bgee; ENSDARG00000057983; Expressed in gastrula and 18 other tissues.
DR   ExpressionAtlas; Q1LVS8; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR005828; MFS_sugar_transport-like.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   Pfam; PF00083; Sugar_tr; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..506
FT                   /note="Putative transporter SVOPL"
FT                   /id="PRO_0000294463"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        297..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        362..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        397..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        444..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        472..492
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        43
FT                   /note="V -> A (in Ref. 2; AAH85429)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        111
FT                   /note="F -> L (in Ref. 2; AAH85429)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        119
FT                   /note="V -> A (in Ref. 2; AAH85429)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   506 AA;  56552 MW;  6DBE9FBCCA667FCD CRC64;
     MALKRSSSMK TQLVDAIQLE EVEMEEEITT TSNNNNPVEP AQVKEPKCYT VEEAVESIGF
     GCFHILLFVI MGSANIVEAM EIMLLAVVSP EIRCEWHLED WQVALVSTMV FFGFMVCGVL
     CGYIADKYGR WKVVFGGFVW ASYFSFLTSF STSYGWFIFL RCMVGCGVAA TSQGFVLKTE
     FIPAKYRAYL LPLASIFWMM GSILIIVLGM TVVPTMGWRW MIRFSVIPSL VLIGLFMFIP
     ESARFQVSAG NIQGAMSTLK RIAKMNNGVL PEGELREPEV TERGNAVTLI SSAFRRTSLL
     LWYSWFVASF SYYGSVLSSS ELLEKNLLCV TDPDLEHQIK HIQEETLCYC IPFNSDDYQT
     LLISCLGEVA LIPLNIILLN IVGRKYSMVI LLLLSAFFFM LVNICTTMLG FTILLFLLRS
     VVSMNFNVVY IYTAEVYPTS VRSIGMGFCT SFSRIGGMIA PFIAQVLMSK SVILALSPFA
     TACIICAIGV FFLPIETRGR ALLQDA