SWAHD_MOUSE
ID SWAHD_MOUSE Reviewed; 327 AA.
AC Q8BY98;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Ankyrin repeat domain-containing protein SOWAHD;
DE AltName: Full=Ankyrin repeat domain-containing protein 58;
DE AltName: Full=Protein sosondowah homolog D;
GN Name=Sowahd; Synonyms=Ankrd58;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Thymus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the SOWAH family. {ECO:0000305}.
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DR EMBL; AK041485; BAC30959.1; -; mRNA.
DR EMBL; AL589767; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC107372; AAI07373.1; -; mRNA.
DR EMBL; BC107373; AAI07374.1; -; mRNA.
DR CCDS; CCDS30067.1; -.
DR RefSeq; NP_776140.1; NM_173779.3.
DR AlphaFoldDB; Q8BY98; -.
DR SMR; Q8BY98; -.
DR IntAct; Q8BY98; 1.
DR STRING; 10090.ENSMUSP00000058152; -.
DR iPTMnet; Q8BY98; -.
DR PhosphoSitePlus; Q8BY98; -.
DR PaxDb; Q8BY98; -.
DR PRIDE; Q8BY98; -.
DR ProteomicsDB; 258783; -.
DR Antibodypedia; 56549; 74 antibodies from 15 providers.
DR Ensembl; ENSMUST00000060057; ENSMUSP00000058152; ENSMUSG00000044400.
DR GeneID; 245381; -.
DR KEGG; mmu:245381; -.
DR UCSC; uc009syb.1; mouse.
DR CTD; 347454; -.
DR MGI; MGI:3045274; Sowahd.
DR VEuPathDB; HostDB:ENSMUSG00000044400; -.
DR eggNOG; ENOG502QPPI; Eukaryota.
DR GeneTree; ENSGT00950000183003; -.
DR HOGENOM; CLU_083908_0_0_1; -.
DR InParanoid; Q8BY98; -.
DR OMA; HMFPFFQ; -.
DR OrthoDB; 1531345at2759; -.
DR PhylomeDB; Q8BY98; -.
DR TreeFam; TF331362; -.
DR BioGRID-ORCS; 245381; 2 hits in 72 CRISPR screens.
DR PRO; PR:Q8BY98; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; Q8BY98; protein.
DR Bgee; ENSMUSG00000044400; Expressed in placenta and 9 other tissues.
DR Gene3D; 1.25.40.20; -; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR Pfam; PF12796; Ank_2; 1.
DR SMART; SM00248; ANK; 2.
DR SUPFAM; SSF48403; SSF48403; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 2: Evidence at transcript level;
KW ANK repeat; Reference proteome; Repeat.
FT CHAIN 1..327
FT /note="Ankyrin repeat domain-containing protein SOWAHD"
FT /id="PRO_0000315706"
FT REPEAT 112..141
FT /note="ANK 1"
FT REPEAT 147..162
FT /note="ANK 2"
FT REPEAT 186..216
FT /note="ANK 3"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 36297 MW; 9595566DF4942E72 CRC64;
MAQALEDGNP LPKASNRPAE SEAPSDPQIK DNHCLGRYKV QAVRDSANLS QERIFHSALT
VSGASWARRR GELRELLGLQ GAAPAGWLSE EHLEPAVPGS RRSSGQGSSR VCLEPREHAW
ILAAAECRFE VLLEMLEAEP SLLMREDPIT GYSVLHWLAK HGRHEELILL HDFARRRGLP
FDVSAPGSGG LTPLHLAALQ GHDMVIKVLV GALGADPSRR DHSGNRPCHY LRPDASLNLR
ELSGAEEWEI ERDRKRENAN NNSSRTTTTT TTTSRWLKRT PSASCIKSTG VHYKEASQPV
KEKKASSTQE GQGRCLRRYL FPFTQNR
