ID   SWC5_CANAL              Reviewed;         338 AA.
AC   Q5A8H7; A0A1D8PQA7;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2017, sequence version 2.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=SWR1-complex protein 5;
GN   Name=SWC5; OrderedLocusNames=CAALFM_C603950CA;
GN   ORFNames=CaO19.13194, CaO19.5772;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC       dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC       transcriptional regulation of selected genes by chromatin remodeling.
CC       Involved in chromosome stability (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the SWR1 chromatin remodeling complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWC5 family. {ECO:0000305}.
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DR   EMBL; CP017628; AOW30321.1; -; Genomic_DNA.
DR   RefSeq; XP_718107.2; XM_713014.2.
DR   AlphaFoldDB; Q5A8H7; -.
DR   STRING; 237561.Q5A8H7; -.
DR   PRIDE; Q5A8H7; -.
DR   GeneID; 3640268; -.
DR   KEGG; cal:CAALFM_C603950CA; -.
DR   CGD; CAL0000185200; orf19.13194.
DR   VEuPathDB; FungiDB:C6_03950C_A; -.
DR   eggNOG; KOG4776; Eukaryota.
DR   HOGENOM; CLU_062474_1_0_1; -.
DR   InParanoid; Q5A8H7; -.
DR   OMA; LDWAAYV; -.
DR   OrthoDB; 1372508at2759; -.
DR   PRO; PR:Q5A8H7; -.
DR   Proteomes; UP000000559; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR   InterPro; IPR011421; BCNT-C.
DR   Pfam; PF07572; BCNT; 1.
DR   PROSITE; PS51279; BCNT_C; 1.
PE   3: Inferred from homology;
KW   Activator; Chromatin regulator; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..338
FT                   /note="SWR1-complex protein 5"
FT                   /id="PRO_0000212503"
FT   DOMAIN          251..331
FT                   /note="BCNT-C"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00610"
FT   REGION          1..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          153..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..49
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..93
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   338 AA;  38842 MW;  FD54586504966CFB CRC64;
     MSKQNIDKST EHSAGENALS EKNHTIESNK NNIDSEEDDE EDEDYDPEKK NEAENEGGVS
     SDEEEDNDQY KDGKTSKIPD YSTIESSTSQ VKTRSQRLHE KLSNQSRFIG NFEVDSKTGL
     VKDQSNIDVN SIFENLKNGS PSIDNSEELN IDSEKTANSQ QQQKQQSNIE ENELQGPKQI
     KIQINYTFAG KLITETKYVD ENSQEAKAYL NSTSNISSSN SNEDIPYRRS QVKVIRTDPV
     TNETKELRIK LKRPSLIDRF LSINGNSKKM KLSTLEKSRL DWASFVDKRN INEELKIHNK
     AGYLDKQDFI NRMNSKRDDL YLQAKEKEKI RKQQLLQK