ID   SWC5_DEBHA              Reviewed;         341 AA.
AC   Q6BWZ7;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=SWR1-complex protein 5;
GN   Name=SWC5; OrderedLocusNames=DEHA2B07216g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC       dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC       transcriptional regulation of selected genes by chromatin remodeling.
CC       Involved in chromosome stability (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the SWR1 chromatin remodeling complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWC5 family. {ECO:0000305}.
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DR   EMBL; CR382134; CAG85273.2; -; Genomic_DNA.
DR   RefSeq; XP_457272.2; XM_457272.1.
DR   AlphaFoldDB; Q6BWZ7; -.
DR   SMR; Q6BWZ7; -.
DR   STRING; 4959.XP_457272.2; -.
DR   EnsemblFungi; CAG85273; CAG85273; DEHA2B07216g.
DR   GeneID; 2913054; -.
DR   KEGG; dha:DEHA2B07216g; -.
DR   VEuPathDB; FungiDB:DEHA2B07216g; -.
DR   eggNOG; KOG4776; Eukaryota.
DR   HOGENOM; CLU_062474_1_0_1; -.
DR   InParanoid; Q6BWZ7; -.
DR   OMA; LDWAAYV; -.
DR   OrthoDB; 1372508at2759; -.
DR   Proteomes; UP000000599; Chromosome B.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   InterPro; IPR011421; BCNT-C.
DR   Pfam; PF07572; BCNT; 1.
DR   PROSITE; PS51279; BCNT_C; 1.
PE   3: Inferred from homology;
KW   Activator; Chromatin regulator; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..341
FT                   /note="SWR1-complex protein 5"
FT                   /id="PRO_0000212505"
FT   DOMAIN          252..331
FT                   /note="BCNT-C"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00610"
FT   REGION          1..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          125..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          316..341
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..33
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..60
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..150
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..180
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        316..333
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   341 AA;  38821 MW;  8953416D59617F31 CRC64;
     MGKQKATRVN GILKKEEQTI DDDSLKKEKQ AIDDEDYDED EDEDYDPEAK VEEEKEASDE
     ESDHEPQPDY SSIENATFQD RLVKTRSQRH QEKYGSNAGI NHIRPGLIKS DDISKNIDVD
     AIFNDLQRKS KSGTPDDWKA SIEEEQAKTE SIKYNNANSK QTTNISSADT PQEDNSLDPQ
     KVKIESSYTF AGKVITESKL VDAGSAEAKA YFNSTKGITA SNLKASAATR SFVPIIRTIP
     GSTEPTELRI KLKRPSLIDK FLSTYGDKKQ KLSTLEKSRL DWASFVDQKK LKDDLSTHNK
     GGYLDKQEFL GRLQDKRDEH YQKAKEEERK RQWQSQQQQS L