ID   SWC5_USTMA              Reviewed;         354 AA.
AC   Q4P6D5; A0A0D1CK39;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-SEP-2015, sequence version 2.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=SWR1-complex protein 5;
GN   Name=SWC5; ORFNames=UMAG_11753;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC       dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC       transcriptional regulation of selected genes by chromatin remodeling.
CC       Involved in chromosome stability (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the SWR1 chromatin remodeling complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWC5 family. {ECO:0000305}.
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DR   EMBL; CM003153; KIS67223.1; -; Genomic_DNA.
DR   RefSeq; XP_011391201.1; XM_011392899.1.
DR   AlphaFoldDB; Q4P6D5; -.
DR   STRING; 5270.UM04328P0; -.
DR   EnsemblFungi; KIS67223; KIS67223; UMAG_11753.
DR   GeneID; 23567602; -.
DR   KEGG; uma:UMAG_11753; -.
DR   VEuPathDB; FungiDB:UMAG_11753; -.
DR   eggNOG; KOG4776; Eukaryota.
DR   HOGENOM; CLU_918668_0_0_1; -.
DR   InParanoid; Q4P6D5; -.
DR   OrthoDB; 1602847at2759; -.
DR   Proteomes; UP000000561; Chromosome 14.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000812; C:Swr1 complex; IBA:GO_Central.
DR   GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR   InterPro; IPR011421; BCNT-C.
DR   InterPro; IPR027124; Swc5/CFDP1/2.
DR   PANTHER; PTHR23227; PTHR23227; 1.
DR   Pfam; PF07572; BCNT; 1.
DR   PROSITE; PS51279; BCNT_C; 1.
PE   3: Inferred from homology;
KW   Activator; Chromatin regulator; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..354
FT                   /note="SWR1-complex protein 5"
FT                   /id="PRO_0000212511"
FT   DOMAIN          272..354
FT                   /note="BCNT-C"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00610"
FT   REGION          1..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          109..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          222..292
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..127
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        222..262
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..292
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   354 AA;  37533 MW;  B08A176C4C79C8EB CRC64;
     MHSIANSSAP VSRSVRDMPN SGSDSDDDDD FVPDAEPSHT AVVRSGLSKQ GKDAVVATDD
     PSDSDSDSDA DGAHSETQDK PAGASVRAAE QIDADELEAL RKEREELVAA AGGEQRLGKR
     RRLAHVSESG ADNQVTNDNE VQALKAKAAA EWEAIKASES GSSMNEQVTQ STATGDYASA
     TTLASTARQE MVSIPTTYKF AGELHTSMRL LPRSHPDALK YLSSQIASPT STTSSAPAPS
     ASASAPLPTS PASTSTSSSP SRPQPARPTP RRKKPSSLSA LSAAATTKPT KLNTLEKSKL
     DWDTYKSDHS QLSQQELDEL EHQTKRGGKG LGDMKGYLDR SDFLDRVKNR TAQP