ID   SWC5_YARLI              Reviewed;         194 AA.
AC   Q6C7G8;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=SWR1-complex protein 5;
GN   Name=SWC5; OrderedLocusNames=YALI0E00946g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC       dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC       transcriptional regulation of selected genes by chromatin remodeling.
CC       Involved in chromosome stability (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the SWR1 chromatin remodeling complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWC5 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR382131; CAG78973.1; -; Genomic_DNA.
DR   RefSeq; XP_503394.1; XM_503394.1.
DR   AlphaFoldDB; Q6C7G8; -.
DR   STRING; 4952.CAG78973; -.
DR   EnsemblFungi; CAG78973; CAG78973; YALI0_E00946g.
DR   GeneID; 2912932; -.
DR   KEGG; yli:YALI0E00946g; -.
DR   VEuPathDB; FungiDB:YALI0_E00946g; -.
DR   HOGENOM; CLU_1403442_0_0_1; -.
DR   InParanoid; Q6C7G8; -.
DR   OMA; WADFQAS; -.
DR   Proteomes; UP000001300; Chromosome E.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   InterPro; IPR011421; BCNT-C.
DR   Pfam; PF07572; BCNT; 1.
DR   PROSITE; PS51279; BCNT_C; 1.
PE   3: Inferred from homology;
KW   Activator; Chromatin regulator; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..194
FT                   /note="SWR1-complex protein 5"
FT                   /id="PRO_0000212512"
FT   DOMAIN          133..194
FT                   /note="BCNT-C"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00610"
FT   REGION          1..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          171..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..65
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..128
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..156
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   194 AA;  21448 MW;  6E961FF55FD65AD6 CRC64;
     MTNEDLLSDS ENDEDFAYKS DKEEDFSDSD DESRKLQRRI DAENKQAMAK EEVKVDKDAM
     RKIYEEMKSG SGAANEIKPV TVKKPDVTTT QTTQQETAST TPTASTTSTT TSTTSAPAPA
     SIPSSAATNK VKKPKRPKKG SLLDAMNKPK KKLNTLEQSK ADWGAFVDKE GIGHDLSQHN
     KDGYLEKRDF LDTH