SWC7_ASHGO
ID SWC7_ASHGO Reviewed; 127 AA.
AC Q757G5;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=SWR1-complex protein 7;
GN Name=SWC7; OrderedLocusNames=AER048C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC transcriptional regulation of selected genes by chromatin remodeling.
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the SWR1 chromatin remodeling complex.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SWC7 family. {ECO:0000305}.
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DR EMBL; AE016818; AAS52732.1; -; Genomic_DNA.
DR RefSeq; NP_984908.1; NM_210262.1.
DR AlphaFoldDB; Q757G5; -.
DR STRING; 33169.AAS52732; -.
DR EnsemblFungi; AAS52732; AAS52732; AGOS_AER048C.
DR GeneID; 4621110; -.
DR KEGG; ago:AGOS_AER048C; -.
DR eggNOG; ENOG502S4GP; Eukaryota.
DR HOGENOM; CLU_157410_0_0_1; -.
DR InParanoid; Q757G5; -.
DR OMA; TLANHYY; -.
DR Proteomes; UP000000591; Chromosome V.
DR GO; GO:0000812; C:Swr1 complex; IEA:EnsemblFungi.
DR GO; GO:0006338; P:chromatin remodeling; IEA:EnsemblFungi.
DR InterPro; IPR020195; SWR1_Swc7.
DR Pfam; PF17330; SWC7; 1.
PE 3: Inferred from homology;
KW Activator; Chromatin regulator; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..127
FT /note="SWR1-complex protein 7"
FT /id="PRO_0000076347"
SQ SEQUENCE 127 AA; 14565 MW; CBEB2BD52D5E9D5C CRC64;
MEYKYNVTLL LLQVVLHRQQ ELAHQDKTLS QISLLREPVV DTAVLERFSA HRVVRLYAPE
LCGLRLEELQ AVVREVFARG LAGSAEDTPV TLITLANHYY RLRVQELELQ ELPKLKELME
SAAGLRT