ID   SWC7_KLULA              Reviewed;         125 AA.
AC   Q6CPF9;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=SWR1-complex protein 7;
GN   Name=SWC7; OrderedLocusNames=KLLA0E05159g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the SWR1 complex which mediates the ATP-
CC       dependent exchange of histone H2A for the H2A variant HZT1 leading to
CC       transcriptional regulation of selected genes by chromatin remodeling.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the SWR1 chromatin remodeling complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWC7 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99267.1; -; Genomic_DNA.
DR   RefSeq; XP_454180.1; XM_454180.1.
DR   AlphaFoldDB; Q6CPF9; -.
DR   STRING; 28985.XP_454180.1; -.
DR   EnsemblFungi; CAG99267; CAG99267; KLLA0_E05215g.
DR   GeneID; 2894099; -.
DR   KEGG; kla:KLLA0_E05215g; -.
DR   eggNOG; ENOG502S4GP; Eukaryota.
DR   HOGENOM; CLU_157410_0_0_1; -.
DR   InParanoid; Q6CPF9; -.
DR   OMA; TLANHYY; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0000812; C:Swr1 complex; IEA:EnsemblFungi.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:EnsemblFungi.
DR   InterPro; IPR020195; SWR1_Swc7.
DR   Pfam; PF17330; SWC7; 1.
PE   3: Inferred from homology;
KW   Activator; Chromatin regulator; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..125
FT                   /note="SWR1-complex protein 7"
FT                   /id="PRO_0000076349"
SQ   SEQUENCE   125 AA;  14399 MW;  CBC58F83387B0CE1 CRC64;
     MSTQNDSIAL LLLQITLYHQ QELAHADSSL SLDELLVEPI VDNTVVEKFT SHSMVQIYAP
     ELAPLNIRSI KGLISDLFTN TNIQEPKNLI TLANHYYSER LNYLQEEKIP ELIQQMKDEY
     RKLAE