SWEET_BRADU
ID SWEET_BRADU Reviewed; 86 AA.
AC Q89G85;
DT 01-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Sugar transporter SemiSWEET {ECO:0000303|PubMed:24027245};
GN OrderedLocusNames=bsr6460 {ECO:0000312|EMBL:BAC51725.1};
OS Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS NBRC 14792 / USDA 110).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Bradyrhizobiaceae; Bradyrhizobium.
OX NCBI_TaxID=224911;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110
RC {ECO:0000312|Proteomes:UP000002526};
RX PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT Bradyrhizobium japonicum USDA110.";
RL DNA Res. 9:189-197(2002).
RN [2]
RP FUNCTION, SUBUNIT, AND SUBCELLULAR LOCATION.
RX PubMed=24027245; DOI=10.1073/pnas.1311244110;
RA Xuan Y.H., Hu Y.B., Chen L.-Q., Sosso D., Ducat D.C., Hou B.-H.,
RA Frommer W.B.;
RT "Functional role of oligomerization for bacterial and plant SWEET sugar
RT transporter family.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:E3685-E3685(2013).
RN [3]
RP SUBUNIT.
RX PubMed=25186729; DOI=10.1038/nature13670;
RA Xu Y., Tao Y., Cheung L.S., Fan C., Chen L.Q., Xu S., Perry K.,
RA Frommer W.B., Feng L.;
RT "Structures of bacterial homologues of SWEET transporters in two distinct
RT conformations.";
RL Nature 515:448-452(2014).
CC -!- FUNCTION: Mediates sucrose transmembrane transport down a concentration
CC gradient. {ECO:0000269|PubMed:24027245}.
CC -!- SUBUNIT: Homodimer (PubMed:25186729). Homooligomer (Probable).
CC {ECO:0000269|PubMed:25186729, ECO:0000305|PubMed:24027245}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:24027245};
CC Multi-pass membrane protein {ECO:0000305}.
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DR EMBL; BA000040; BAC51725.1; -; Genomic_DNA.
DR RefSeq; NP_773100.1; NC_004463.1.
DR RefSeq; WP_011089200.1; NZ_CP011360.1.
DR AlphaFoldDB; Q89G85; -.
DR SMR; Q89G85; -.
DR DIP; DIP-61076N; -.
DR STRING; 224911.27354739; -.
DR TCDB; 2.A.123.2.14; the sweet, pq-loop, saliva, mtn3 (sweet) family.
DR EnsemblBacteria; BAC51725; BAC51725; BAC51725.
DR GeneID; 64026214; -.
DR KEGG; bja:bsr6460; -.
DR PATRIC; fig|224911.44.peg.6450; -.
DR eggNOG; COG4095; Bacteria.
DR HOGENOM; CLU_135915_1_1_5; -.
DR InParanoid; Q89G85; -.
DR OMA; WIIYGYK; -.
DR Proteomes; UP000002526; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR006603; PQ-loop_rpt.
DR Pfam; PF04193; PQ-loop; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..86
FT /note="Sugar transporter SemiSWEET"
FT /id="PRO_0000432580"
FT TRANSMEM 3..23
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..57
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..81
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT DOMAIN 6..63
FT /note="PQ-loop"
FT /evidence="ECO:0000255"
SQ SEQUENCE 86 AA; 9191 MW; B9B98697D87D5069 CRC64;
MDPFLIKLIG FAAATCTTVA YAPQFIKVLK TRSARDISLG MFLVMVLGLA LWLIYGLLSG
DAPLIASNAV TMLLAGGILV MKLRYG
