SWET1_CAEBR
ID SWET1_CAEBR Reviewed; 293 AA.
AC A8XI14;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Sugar transporter SWEET1;
GN Name=swt-1; ORFNames=CBG13500;
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16;
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R.M., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the membrane. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000305}.
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DR EMBL; HE600980; CAP32287.1; -; Genomic_DNA.
DR RefSeq; XP_002634964.1; XM_002634918.1.
DR AlphaFoldDB; A8XI14; -.
DR SMR; A8XI14; -.
DR STRING; 6238.CBG13500; -.
DR EnsemblMetazoa; CBG13500.1; CBG13500.1; WBGene00034257.
DR GeneID; 8576958; -.
DR KEGG; cbr:CBG_13500; -.
DR CTD; 8576958; -.
DR WormBase; CBG13500; CBP03306; WBGene00034257; Cbr-swt-1.
DR eggNOG; KOG1623; Eukaryota.
DR HOGENOM; CLU_048643_3_1_1; -.
DR InParanoid; A8XI14; -.
DR OMA; KEHVVNI; -.
DR OrthoDB; 1116261at2759; -.
DR Proteomes; UP000008549; Chromosome IV.
DR GO; GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; ISS:UniProtKB.
DR GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR InterPro; IPR004316; SWEET_sugar_transpr.
DR Pfam; PF03083; MtN3_slv; 2.
PE 3: Inferred from homology;
KW Cell membrane; Golgi apparatus; Membrane; Reference proteome; Repeat;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..293
FT /note="Sugar transporter SWEET1"
FT /id="PRO_0000345124"
FT TRANSMEM 8..28
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 36..56
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 95..115
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..200
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT DOMAIN 7..91
FT /note="MtN3/slv 1"
FT DOMAIN 121..205
FT /note="MtN3/slv 2"
FT REGION 225..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 293 AA; 32597 MW; 818376D8854BB6CD CRC64;
MIEVVLQVLS ISAITTTIAL FFCGIPICMQ IRRQGAVGDI SGVPFLMGVL GGSFWLRYGL
LKMDYTMIIV NVVGVFCMAV YCIFFLIYSL PKKTFTCQLI LVTSTITGMV VWIAFKPNLD
YLGIICMTFN IMNFGAPLAG LGVVLRNREV STLPLPMCVA NFLVSSQWCL YGNLVQDIYI
IIPNGIGMFL AIVQLSLFIV LPRRENEKSP LEQLANWFTG RDRNKKEKDL ETGECAEPSS
PQKIPSDVHE KLEKLMAAEA SSESRRCSAD FMDHPPSYKS RSSSVPDIFS VQS
