ID   SWET1_XENTR             Reviewed;         214 AA.
AC   Q5EAL3;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Sugar transporter SWEET1;
DE   AltName: Full=Solute carrier family 50 member 1;
GN   Name=slc50a1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates sugar transport across membranes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC090379; AAH90379.1; -; mRNA.
DR   RefSeq; NP_001015865.1; NM_001015865.1.
DR   AlphaFoldDB; Q5EAL3; -.
DR   SMR; Q5EAL3; -.
DR   STRING; 8364.ENSXETP00000042092; -.
DR   PaxDb; Q5EAL3; -.
DR   DNASU; 548582; -.
DR   GeneID; 548582; -.
DR   KEGG; xtr:548582; -.
DR   CTD; 55974; -.
DR   Xenbase; XB-GENE-970558; slc50a1.
DR   eggNOG; KOG1623; Eukaryota.
DR   InParanoid; Q5EAL3; -.
DR   OrthoDB; 1116261at2759; -.
DR   Reactome; R-XTR-189200; Cellular hexose transport.
DR   Proteomes; UP000008143; Chromosome 8.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051119; F:sugar transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR   InterPro; IPR004316; SWEET_sugar_transpr.
DR   Pfam; PF03083; MtN3_slv; 2.
PE   2: Evidence at transcript level;
KW   Cell membrane; Golgi apparatus; Membrane; Reference proteome; Repeat;
KW   Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..214
FT                   /note="Sugar transporter SWEET1"
FT                   /id="PRO_0000345121"
FT   TRANSMEM        3..23
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..85
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..145
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..177
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..201
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          6..89
FT                   /note="MtN3/slv 1"
FT   DOMAIN          124..207
FT                   /note="MtN3/slv 2"
SQ   SEQUENCE   214 AA;  24296 MW;  959CDD0FEC64D6FC CRC64;
     MDWMWLLSGA CIVFTLGMFS SGLSDLRVMV AKRSVENIQF LPFLTTDLNN LGWFYYGYLK
     GDGTLIIVNL IGASLQTLYM AAYILYSLER RYVVSQVLVS LGVLFLAHCY FTLWTPDINS
     RLNQLGLFCS IFTISMYLSP LADLAQIIKS KSTKCLSFPL TVATFLTSTS WVLYGWVQSD
     LYITVPNFPG IVTSLLRFWL FSRYPPDQPA YSLL