SWET4_ORYSI
ID SWET4_ORYSI Reviewed; 259 AA.
AC A2X3S3; A6N106;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Bidirectional sugar transporter SWEET4;
DE Short=OsSWEET4;
GN Name=SWEET4; ORFNames=OsI_06860;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 119-259.
RC TISSUE=Shoot;
RA Kumari S., Panjabi V., Singla-Pareek S.L., Sopory S.K., Pareek A.;
RT "A comparative transcriptome map of early and late salinity stress
RT responses in contrasting genotypes of Oryza sativa L.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the plasma membrane. {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SUBUNIT: Forms homooligomers and/or heterooligomers.
CC {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8L9J7};
CC Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000305}.
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DR EMBL; CM000127; EAY85483.1; -; Genomic_DNA.
DR EMBL; EF576338; ABR25926.1; -; mRNA.
DR AlphaFoldDB; A2X3S3; -.
DR SMR; A2X3S3; -.
DR STRING; 39946.A2X3S3; -.
DR EnsemblPlants; BGIOSGA006640-TA; BGIOSGA006640-PA; BGIOSGA006640.
DR Gramene; BGIOSGA006640-TA; BGIOSGA006640-PA; BGIOSGA006640.
DR HOGENOM; CLU_048643_1_0_1; -.
DR OMA; CTCAGFI; -.
DR Proteomes; UP000007015; Chromosome 2.
DR GO; GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; ISS:UniProtKB.
DR InterPro; IPR004316; SWEET_sugar_transpr.
DR Pfam; PF03083; MtN3_slv; 2.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; Membrane; Reference proteome; Repeat;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..259
FT /note="Bidirectional sugar transporter SWEET4"
FT /id="PRO_0000404142"
FT TOPO_DOM 1..10
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 11..31
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 32..44
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 45..65
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 66..77
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 78..98
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 99..101
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 123..131
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 132..152
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 153..165
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 166..186
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 187..191
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 192..212
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 213..259
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 10..94
FT /note="MtN3/slv 1"
FT DOMAIN 133..217
FT /note="MtN3/slv 2"
FT CARBOHYD 76
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 259 AA; 28046 MW; 44B6A1509C0EADFC CRC64;
MVSPDTIRTA IGVVGNGTAL VLFLSPVPTF IRIWKKGSVE QYSAVPYVAT LLNCMMWVLY
GLPAVHPHSM LVITINGTGM AIELTYIALF LAFSLGAVRR RVLLLLAAEV AFVAAVAALV
LNLAHTHERR SMIVGILCVL FGTGMYAAPL SVMKMVIQTK SVEYMPLFLS LASLVNGICW
TAYALIRFDL YITIPNGLGV MFAVAQLILY AIYYKSTQQI IEARKRKEAD HVAMTDVVVD
SAKNNPSSGA AAAAANGRY
