SWI5_RAT
ID SWI5_RAT Reviewed; 89 AA.
AC Q63ZV7;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=DNA repair protein SWI5 homolog;
DE AltName: Full=Protein SAE3 homolog;
GN Name=Swi5; Synonyms=Sae3;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Component of the SWI5-SFR1 complex, a complex required for
CC double-strand break repair via homologous recombination. {ECO:0000250}.
CC -!- SUBUNIT: Component of the SWI5-SFR1 complex. Interacts with RAD51 (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SWI5/SAE3 family. {ECO:0000305}.
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DR EMBL; BC082799; AAH82799.1; -; mRNA.
DR RefSeq; NP_001233590.1; NM_001246661.1.
DR AlphaFoldDB; Q63ZV7; -.
DR SMR; Q63ZV7; -.
DR STRING; 10116.ENSRNOP00000029603; -.
DR iPTMnet; Q63ZV7; -.
DR PhosphoSitePlus; Q63ZV7; -.
DR jPOST; Q63ZV7; -.
DR PaxDb; Q63ZV7; -.
DR PRIDE; Q63ZV7; -.
DR GeneID; 499779; -.
DR KEGG; rno:499779; -.
DR UCSC; RGD:1559966; rat.
DR CTD; 375757; -.
DR RGD; 1559966; Swi5.
DR VEuPathDB; HostDB:ENSRNOG00000022860; -.
DR eggNOG; ENOG502S8Z3; Eukaryota.
DR HOGENOM; CLU_106110_1_1_1; -.
DR InParanoid; Q63ZV7; -.
DR OMA; HEYDDIK; -.
DR OrthoDB; 1553901at2759; -.
DR PhylomeDB; Q63ZV7; -.
DR TreeFam; TF336078; -.
DR PRO; PR:Q63ZV7; -.
DR Proteomes; UP000002494; Chromosome 3.
DR Bgee; ENSRNOG00000022860; Expressed in testis and 20 other tissues.
DR Genevisible; Q63ZV7; RN.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0032798; C:Swi5-Sfr1 complex; ISS:UniProtKB.
DR GO; GO:0034974; C:Swi5-Swi2 complex; IBA:GO_Central.
DR GO; GO:0071479; P:cellular response to ionizing radiation; ISS:UniProtKB.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.
DR InterPro; IPR010760; DNA-repair_Swi5.
DR PANTHER; PTHR28529; PTHR28529; 1.
DR Pfam; PF07061; Swi5; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA damage; DNA repair; Nucleus; Reference proteome.
FT CHAIN 1..89
FT /note="DNA repair protein SWI5 homolog"
FT /id="PRO_0000324586"
FT COILED 7..37
FT /evidence="ECO:0000255"
SQ SEQUENCE 89 AA; 10279 MW; B377F04AAEF879C3 CRC64;
MIDEGEEVTE ETLNSDIQKL KEKQDMLDKE ISQLIAEGYR VIELEQHISL LHEYNDIKDV
SQMLLGKLAV TRGVTTKELY PDFDLNPND