SWI5_SALSA
ID SWI5_SALSA Reviewed; 138 AA.
AC B5X601;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 25-NOV-2008, sequence version 1.
DT 03-AUG-2022, entry version 27.
DE RecName: Full=DNA repair protein SWI5 homolog;
DE AltName: Full=Protein SAE3 homolog;
GN Name=swi5; Synonyms=sae3;
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Head kidney;
RX PubMed=20433749; DOI=10.1186/1471-2164-11-279;
RA Leong J.S., Jantzen S.G., von Schalburg K.R., Cooper G.A., Messmer A.M.,
RA Liao N.Y., Munro S., Moore R., Holt R.A., Jones S.J., Davidson W.S.,
RA Koop B.F.;
RT "Salmo salar and Esox lucius full-length cDNA sequences reveal changes in
RT evolutionary pressures on a post-tetraploidization genome.";
RL BMC Genomics 11:279-279(2010).
CC -!- FUNCTION: Component of the swi5-sfr1 complex, a complex required for
CC double-strand break repair via homologous recombination. {ECO:0000250}.
CC -!- SUBUNIT: Component of the swi5-sfr1 complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SWI5/SAE3 family. {ECO:0000305}.
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DR EMBL; BT046470; ACI66271.1; -; mRNA.
DR RefSeq; NP_001134113.1; NM_001140641.1.
DR AlphaFoldDB; B5X601; -.
DR SMR; B5X601; -.
DR GeneID; 100195612; -.
DR KEGG; sasa:100195612; -.
DR CTD; 375757; -.
DR OMA; LEHHINM; -.
DR OrthoDB; 1553901at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR Bgee; ENSSSAG00000010881; Expressed in testis and 15 other tissues.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0032798; C:Swi5-Sfr1 complex; ISS:UniProtKB.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.
DR InterPro; IPR010760; DNA-repair_Swi5.
DR PANTHER; PTHR28529; PTHR28529; 1.
DR Pfam; PF07061; Swi5; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; DNA damage; DNA repair; Nucleus; Reference proteome.
FT CHAIN 1..138
FT /note="DNA repair protein SWI5 homolog"
FT /id="PRO_0000406980"
FT REGION 21..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 60..87
FT /evidence="ECO:0000255"
FT COMPBIAS 39..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 138 AA; 15308 MW; AD7CCB6BEB988FC1 CRC64;
MDTERSSEIC GNVPDVTLST PKGKVFSTPK GAHKRTPYSG HTKVNSSFKS PVQTSSTSPA
KPEEEIEELK KRRAKLDSEI ALLEKDGIRV DELEQHIDLL HEYNDIKDIG QSLVGRIAAL
RGVTTRDLYG QFGLELDD