ID   SWI5_XENTR              Reviewed;         105 AA.
AC   A9UL70; B7ZUG6;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-APR-2011, sequence version 2.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=DNA repair protein SWI5 homolog;
DE   AltName: Full=Protein SAE3 homolog;
GN   Name=swi5; Synonyms=sae3;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Neurula;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the swi5-sfr1 complex, a complex required for
CC       double-strand break repair via homologous recombination. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the swi5-sfr1 complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWI5/SAE3 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC157143; AAI57144.1; -; mRNA.
DR   EMBL; BC171224; AAI71224.1; -; mRNA.
DR   EMBL; BC171226; AAI71226.1; -; mRNA.
DR   RefSeq; NP_001107337.1; NM_001113865.1.
DR   AlphaFoldDB; A9UL70; -.
DR   SMR; A9UL70; -.
DR   STRING; 8364.ENSXETP00000015579; -.
DR   PaxDb; A9UL70; -.
DR   GeneID; 100135158; -.
DR   KEGG; xtr:100135158; -.
DR   CTD; 375757; -.
DR   Xenbase; XB-GENE-6257718; swi5.
DR   eggNOG; ENOG502S8Z3; Eukaryota.
DR   HOGENOM; CLU_2533474_0_0_1; -.
DR   InParanoid; A9UL70; -.
DR   OrthoDB; 1553901at2759; -.
DR   Proteomes; UP000008143; Chromosome 8.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000007174; Expressed in testis and 12 other tissues.
DR   ExpressionAtlas; A9UL70; baseline and differential.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0032798; C:Swi5-Sfr1 complex; ISS:UniProtKB.
DR   GO; GO:0034974; C:Swi5-Swi2 complex; IBA:GO_Central.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.
DR   InterPro; IPR010760; DNA-repair_Swi5.
DR   PANTHER; PTHR28529; PTHR28529; 1.
DR   Pfam; PF07061; Swi5; 1.
PE   3: Inferred from homology;
KW   Coiled coil; DNA damage; DNA repair; Nucleus; Reference proteome.
FT   CHAIN           1..105
FT                   /note="DNA repair protein SWI5 homolog"
FT                   /id="PRO_0000324587"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          28..54
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        8..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        6
FT                   /note="N -> K (in Ref. 1; AAI57144)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        97
FT                   /note="A -> V (in Ref. 1; AAI57144)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   105 AA;  11640 MW;  07CB004FA47F3673 CRC64;
     MRRNCNAGFK SPVQSPSSSS SGRGSEYSLQ KEVSELQGKE AALDQEIAQL ESEGFSMAEL
     EEHITLLHEY NELKDVGQML LGRLAVLRGV TTKELYAEFG MNLED