SWT11_ORYSJ
ID SWT11_ORYSJ Reviewed; 307 AA.
AC Q6YZF3; A0A0P0XIY5; K4FDI0;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Bidirectional sugar transporter SWEET11;
DE Short=OsSWEET11;
DE AltName: Full=Disease resistant allele Xa13;
GN Name=SWEET11; Synonyms=Os8N3, XA13;
GN OrderedLocusNames=Os08g0535200, LOC_Os08g42350;
GN ORFNames=OsJ_28080, OSJNBa0033D24.17, P0702C09.32;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Ilpoombyeo; TISSUE=Immature seed;
RA Yoon U.H.;
RT "Structural and expression analysis of immature seed genes in Oryza sativa
RT L.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RC STRAIN=cv. Indica / IR24, and cv. Indica / IRBB13;
RX PubMed=16648463; DOI=10.1101/gad.1416306;
RA Chu Z., Yuan M., Yao J., Ge X., Yuan B., Xu C., Li X., Fu B., Li Z.,
RA Bennetzen J.L., Zhang Q., Wang S.;
RT "Promoter mutations of an essential gene for pollen development result in
RT disease resistance in rice.";
RL Genes Dev. 20:1250-1255(2006).
RN [8]
RP FUNCTION, INDUCTION BY XANTHOMONAS ORYZAE, AND TISSUE SPECIFICITY.
RC STRAIN=cv. BJ1, cv. Indica / IR24, cv. Indica / IRBB13, cv. Juma, and
RC cv. Nipponbare;
RX PubMed=16798873; DOI=10.1073/pnas.0604088103;
RA Yang B., Sugio A., White F.F.;
RT "Os8N3 is a host disease-susceptibility gene for bacterial blight of
RT rice.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:10503-10508(2006).
RN [9]
RP FUNCTION, INDUCTION BY XANTHOMONAS ORYZAE, AND TISSUE SPECIFICITY.
RX PubMed=19318375; DOI=10.1093/pcp/pcp046;
RA Yuan M., Chu Z., Li X., Xu C., Wang S.;
RT "Pathogen-induced expressional loss of function is the key factor in race-
RT specific bacterial resistance conferred by a recessive R gene xa13 in
RT rice.";
RL Plant Cell Physiol. 50:947-955(2009).
RN [10]
RP FUNCTION, DISRUPTION PHENOTYPE, SUBCELLULAR LOCATION, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=21107422; DOI=10.1038/nature09606;
RA Chen L.-Q., Hou B.-H., Lalonde S., Takanaga H., Hartung M.L., Qu X.-Q.,
RA Guo W.-J., Kim J.-G., Underwood W., Chaudhuri B., Chermak D., Antony G.,
RA White F.F., Somerville S.C., Mudgett M.B., Frommer W.B.;
RT "Sugar transporters for intercellular exchange and nutrition of
RT pathogens.";
RL Nature 468:527-532(2010).
RN [11]
RP INDUCTION BY PTHXO1.
RC STRAIN=cv. Indica / IR24, and cv. Indica / IRBB13;
RX PubMed=20345643; DOI=10.1111/j.1469-8137.2010.03217.x;
RA Roemer P., Recht S., Strauss T., Elsaesser J., Schornack S., Boch J.,
RA Wang S., Lahaye T.;
RT "Promoter elements of rice susceptibility genes are bound and activated by
RT specific TAL effectors from the bacterial blight pathogen, Xanthomonas
RT oryzae pv. oryzae.";
RL New Phytol. 187:1048-1057(2010).
RN [12]
RP FUNCTION, INTERACTION WITH COPT1 AND COPT2, AND SUBCELLULAR LOCATION.
RX PubMed=20852017; DOI=10.1105/tpc.110.078022;
RA Antony G., Zhou J., Huang S., Li T., Liu B., White F., Yang B., Yuan M.,
RA Chu Z., Li X., Xu C., Wang S.;
RT "Rice xa13 recessive resistance to bacterial blight is defeated by
RT induction of the disease susceptibility gene Os-11N3. The bacterial
RT pathogen Xanthomonas oryzae overcomes rice defenses by regulating host
RT copper redistribution.";
RL Plant Cell 22:3164-3176(2010).
RN [13]
RP REVIEW.
RX PubMed=22815540; DOI=10.1093/mp/sss054;
RA Baker R.F., Leach K.A., Braun D.M.;
RT "SWEET as sugar: new sucrose effluxers in plants.";
RL Mol. Plant 5:766-768(2012).
RN [14]
RP FUNCTION.
RX PubMed=22157085; DOI=10.1126/science.1213351;
RA Chen L.-Q., Qu X.-Q., Hou B.-H., Sosso D., Osorio S., Fernie A.R.,
RA Frommer W.B.;
RT "Sucrose efflux mediated by SWEET proteins as a key step for phloem
RT transport.";
RL Science 335:207-211(2012).
RN [15]
RP FUNCTION, AND INDUCTION BY TAL PROTEINS.
RC STRAIN=cv. Nipponbare;
RX PubMed=23879865; DOI=10.1111/nph.12411;
RA Streubel J., Pesce C., Hutin M., Koebnik R., Boch J., Szurek B.;
RT "Five phylogenetically close rice SWEET genes confer TAL effector-mediated
RT susceptibility to Xanthomonas oryzae pv. oryzae.";
RL New Phytol. 200:808-819(2013).
RN [16]
RP REVIEW.
RX PubMed=25988582; DOI=10.1016/j.pbi.2015.04.005;
RA Eom J.-S., Chen L.-Q., Sosso D., Julius B.T., Lin I.W., Qu X.-Q.,
RA Braun D.M., Frommer W.B.;
RT "SWEETs, transporters for intracellular and intercellular sugar
RT translocation.";
RL Curr. Opin. Plant Biol. 25:53-62(2015).
RN [17]
RP INTERACTION WITH APX8.
RC STRAIN=cv. Taipei 309;
RX PubMed=27185545; DOI=10.1038/srep26104;
RA Jiang G., Yin D., Zhao J., Chen H., Guo L., Zhu L., Zhai W.;
RT "The rice thylakoid membrane-bound ascorbate peroxidase OsAPX8 functions in
RT tolerance to bacterial blight.";
RL Sci. Rep. 6:26104-26104(2016).
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the plasma membrane. Required for pollen viability. Involved in the
CC transport of copper, in cooperation with COPT1 and COPT2
CC (PubMed:16648463, PubMed:20852017, PubMed:21107422, PubMed:25988582).
CC {ECO:0000269|PubMed:16648463, ECO:0000269|PubMed:20852017,
CC ECO:0000269|PubMed:21107422, ECO:0000269|PubMed:22157085,
CC ECO:0000303|PubMed:25988582}.
CC -!- FUNCTION: Confers sensitivity to bacterial blight mediated by X.oryzae
CC pv. oryzae (Xoo) in its Xa13 allelic form (e.g. cv. IR24), probably by
CC providing the sugar required for the pathogen growth, or by reducing
CC copper contents in xylem. However, a recessive resistance can be
CC associated with the xa13 allele (in which the promoter is mutated
CC leading to reduced induction upon pathogen infection, e.g. cv. IRBB13),
CC specifically toward Xoo Philippine race 6 and Indian race PXO8.
CC {ECO:0000269|PubMed:16648463, ECO:0000269|PubMed:16798873,
CC ECO:0000269|PubMed:19318375, ECO:0000269|PubMed:21107422,
CC ECO:0000269|PubMed:23879865, ECO:0000303|PubMed:25988582}.
CC -!- SUBUNIT: Interacts with COPT1 and COPT2 (PubMed:20852017). Interacts
CC with APX8 (PubMed:27185545). {ECO:0000269|PubMed:20852017,
CC ECO:0000269|PubMed:27185545}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:20852017,
CC ECO:0000269|PubMed:21107422}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:20852017, ECO:0000269|PubMed:21107422}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in panicles and anthers. Also
CC detected in leaves (leaf collar, leaf auricle, leaf ligule), roots,
CC sheaths, culms and culm nodes. {ECO:0000269|PubMed:16648463,
CC ECO:0000269|PubMed:16798873, ECO:0000269|PubMed:19318375}.
CC -!- DEVELOPMENTAL STAGE: Accumulates to high levels in pollen grains,
CC tapetal cells, and middle-layer cells of the anther wall. Also detected
CC at high levels in connective tissue cells and the connective vascular
CC element at the unicellular- to-bicellular pollen grain stages. At the
CC tricellular pollen grain stage, confined to the cells of connective
CC vascular elements. {ECO:0000269|PubMed:16648463}.
CC -!- INDUCTION: By the X.oryzae pv. oryzae (Xoo) transcription activator-
CC like effector (TALe) protein pthXo1 and, possibly, AvrXa7.
CC {ECO:0000269|PubMed:16798873, ECO:0000269|PubMed:19318375,
CC ECO:0000269|PubMed:20345643, ECO:0000269|PubMed:23879865}.
CC -!- DISRUPTION PHENOTYPE: Reduced starch content in pollen and male
CC sterility. Enhanced resistance against bacterial blight mediated by
CC X.oryzae pv. oryzae (Xoo) strain PXO99(A).
CC {ECO:0000269|PubMed:16648463, ECO:0000269|PubMed:21107422}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000305}.
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DR EMBL; JN944367; AFI71278.1; -; mRNA.
DR EMBL; AP005439; BAD13102.1; -; Genomic_DNA.
DR EMBL; AP005528; BAD13168.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF24268.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT06435.1; -; Genomic_DNA.
DR EMBL; CM000145; EEE69066.1; -; Genomic_DNA.
DR EMBL; AK106127; BAG97588.1; -; mRNA.
DR RefSeq; XP_015648423.1; XM_015792937.1.
DR AlphaFoldDB; Q6YZF3; -.
DR SMR; Q6YZF3; -.
DR STRING; 4530.OS08T0535200-01; -.
DR TCDB; 2.A.123.1.6; the sweet, pq-loop, saliva, mtn3 (sweet) family.
DR PaxDb; Q6YZF3; -.
DR PRIDE; Q6YZF3; -.
DR EnsemblPlants; Os08t0535200-01; Os08t0535200-01; Os08g0535200.
DR GeneID; 4346153; -.
DR Gramene; Os08t0535200-01; Os08t0535200-01; Os08g0535200.
DR KEGG; osa:4346153; -.
DR eggNOG; KOG1623; Eukaryota.
DR HOGENOM; CLU_048643_4_0_1; -.
DR InParanoid; Q6YZF3; -.
DR OMA; IVGVHKI; -.
DR OrthoDB; 1116261at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q6YZF3; OS.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; IDA:UniProtKB.
DR GO; GO:0008515; F:sucrose transmembrane transporter activity; IDA:UniProtKB.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; ISS:UniProtKB.
DR GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR GO; GO:0006825; P:copper ion transport; IMP:UniProtKB.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0015770; P:sucrose transport; IDA:UniProtKB.
DR InterPro; IPR004316; SWEET_sugar_transpr.
DR Pfam; PF03083; MtN3_slv; 2.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Plant defense; Reference proteome; Repeat;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..307
FT /note="Bidirectional sugar transporter SWEET11"
FT /id="PRO_0000404133"
FT TOPO_DOM 1..14
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 15..35
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 36..47
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 48..68
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 69..74
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 96..107
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 108..128
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 129..135
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 136..156
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 157..168
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..189
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 190..194
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 195..215
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 216..307
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 17..100
FT /note="MtN3/slv 1"
FT DOMAIN 136..219
FT /note="MtN3/slv 2"
SQ SEQUENCE 307 AA; 32978 MW; 6E505D8DA701B664 CRC64;
MAGGFLSMAN PAVTLSGVAG NIISFLVFLA PVATFLQVYK KKSTGGYSSV PYVVALFSSV
LWIFYALVKT NSRPLLTINA FGCGVEAAYI VLYLVYAPRR ARLRTLAFFL LLDVAAFALI
VVTTLYLVPK PHQVKFLGSV CLAFSMAVFV APLSIIFKVI KTKSVEFMPI GLSVCLTLSA
VAWFCYGLFT KDPYVMYPNV GGFFFSCVQM GLYFWYRKPR NTAVLPTTSD SMSPISAAAA
ATQRVIELPA GTHAFTILSV SPIPILGVHK VEVVAAEQAA DGVAAAAAAD KELLQNKPEV
IEITAAV
