SWT14_ORYSJ
ID SWT14_ORYSJ Reviewed; 303 AA.
AC Q2R3P9; A0A0P0Y2E6;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Bidirectional sugar transporter SWEET14;
DE Short=OsSWEET14;
GN Name=SWEET14; Synonyms=Os11N3;
GN OrderedLocusNames=Os11g0508600, LOC_Os11g31190; ORFNames=OsJ_34008;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP FUNCTION, SUBCELLULAR LOCATION, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=21107422; DOI=10.1038/nature09606;
RA Chen L.-Q., Hou B.-H., Lalonde S., Takanaga H., Hartung M.L., Qu X.-Q.,
RA Guo W.-J., Kim J.-G., Underwood W., Chaudhuri B., Chermak D., Antony G.,
RA White F.F., Somerville S.C., Mudgett M.B., Frommer W.B.;
RT "Sugar transporters for intercellular exchange and nutrition of
RT pathogens.";
RL Nature 468:527-532(2010).
RN [8]
RP INDUCTION BY AVRXA7.
RC STRAIN=cv. Indica / IR24, and cv. Indica / IRBB13;
RX PubMed=20345643; DOI=10.1111/j.1469-8137.2010.03217.x;
RA Roemer P., Recht S., Strauss T., Elsaesser J., Schornack S., Boch J.,
RA Wang S., Lahaye T.;
RT "Promoter elements of rice susceptibility genes are bound and activated by
RT specific TAL effectors from the bacterial blight pathogen, Xanthomonas
RT oryzae pv. oryzae.";
RL New Phytol. 187:1048-1057(2010).
RN [9]
RP REVIEW.
RX PubMed=22815540; DOI=10.1093/mp/sss054;
RA Baker R.F., Leach K.A., Braun D.M.;
RT "SWEET as sugar: new sucrose effluxers in plants.";
RL Mol. Plant 5:766-768(2012).
RN [10]
RP FUNCTION.
RX PubMed=22157085; DOI=10.1126/science.1213351;
RA Chen L.-Q., Qu X.-Q., Hou B.-H., Sosso D., Osorio S., Fernie A.R.,
RA Frommer W.B.;
RT "Sucrose efflux mediated by SWEET proteins as a key step for phloem
RT transport.";
RL Science 335:207-211(2012).
RN [11]
RP FUNCTION, AND INDUCTION BY AVRXA7; PTHXO3 AND TAL5.
RC STRAIN=cv. Nipponbare;
RX PubMed=23879865; DOI=10.1111/nph.12411;
RA Streubel J., Pesce C., Hutin M., Koebnik R., Boch J., Szurek B.;
RT "Five phylogenetically close rice SWEET genes confer TAL effector-mediated
RT susceptibility to Xanthomonas oryzae pv. oryzae.";
RL New Phytol. 200:808-819(2013).
RN [12]
RP REVIEW.
RX PubMed=25988582; DOI=10.1016/j.pbi.2015.04.005;
RA Eom J.-S., Chen L.-Q., Sosso D., Julius B.T., Lin I.W., Qu X.-Q.,
RA Braun D.M., Frommer W.B.;
RT "SWEETs, transporters for intracellular and intercellular sugar
RT translocation.";
RL Curr. Opin. Plant Biol. 25:53-62(2015).
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the plasma membrane. {ECO:0000269|PubMed:21107422,
CC ECO:0000269|PubMed:22157085}.
CC -!- FUNCTION: Confers blight susceptibility (PubMed:25988582). Confers TAL
CC effector-mediated susceptibility to Xanthomonas oryzae pv. oryzae
CC (PubMed:23879865). {ECO:0000269|PubMed:23879865,
CC ECO:0000303|PubMed:25988582}.
CC -!- SUBUNIT: Forms homooligomers and/or heterooligomers.
CC {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:21107422};
CC Multi-pass membrane protein {ECO:0000269|PubMed:21107422}.
CC -!- INDUCTION: By the X.oryzae pv. oryzae (Xoo) transcription activator-
CC like effector (TALe) proteins AvrXa7, PthXo3 and Tal5.
CC {ECO:0000269|PubMed:20345643, ECO:0000269|PubMed:23879865}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000305}.
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DR EMBL; DP000010; ABA93969.1; -; Genomic_DNA.
DR EMBL; AP008217; BAF28318.1; -; Genomic_DNA.
DR EMBL; AP014967; BAT14161.1; -; Genomic_DNA.
DR EMBL; CM000148; EAZ18482.1; -; Genomic_DNA.
DR EMBL; AK101913; BAG95290.1; -; mRNA.
DR RefSeq; XP_015615538.1; XM_015760052.1.
DR AlphaFoldDB; Q2R3P9; -.
DR SMR; Q2R3P9; -.
DR STRING; 4530.OS11T0508600-01; -.
DR PaxDb; Q2R3P9; -.
DR PRIDE; Q2R3P9; -.
DR EnsemblPlants; Os11t0508600-01; Os11t0508600-01; Os11g0508600.
DR GeneID; 4350572; -.
DR Gramene; Os11t0508600-01; Os11t0508600-01; Os11g0508600.
DR KEGG; osa:4350572; -.
DR eggNOG; KOG1623; Eukaryota.
DR HOGENOM; CLU_048643_4_0_1; -.
DR InParanoid; Q2R3P9; -.
DR OMA; KEHVVNI; -.
DR OrthoDB; 1116261at2759; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000007752; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR Genevisible; Q2R3P9; OS.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB.
DR GO; GO:0008515; F:sucrose transmembrane transporter activity; IDA:UniProtKB.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; ISS:UniProtKB.
DR GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR GO; GO:0015770; P:sucrose transport; IDA:UniProtKB.
DR InterPro; IPR004316; SWEET_sugar_transpr.
DR Pfam; PF03083; MtN3_slv; 2.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Repeat; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..303
FT /note="Bidirectional sugar transporter SWEET14"
FT /id="PRO_0000404136"
FT TOPO_DOM 1..9
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 10..30
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 31..44
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 45..65
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 66..72
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 73..93
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 94..105
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..126
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 127..133
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 155..167
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 168..188
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 189..192
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 214..303
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 13..98
FT /note="MtN3/slv 1"
FT DOMAIN 134..217
FT /note="MtN3/slv 2"
FT REGION 266..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 303 AA; 32701 MW; 1EFF0EC051E52312 CRC64;
MAGMSLQHPW AFAFGLLGNI ISFMTYLAPL PTFYRIYKSK STQGFQSVPY VVALFSAMLW
IYYALLKSDE CLLITINSAG CVIETIYIAV YLVYAPKKAK MFTAKLLLLV NVGVFGLILL
LTLLLSAGDR RIVVLGWVCV GFSVSVFVAP LSIIRLVVRT KSVEFMPFSL SFSLTISAVV
WFLYGLLIKD KYVALPNVLG FSFGVIQMGL YAMYRNSTPK AVLTKEVEAA TATGDDDHSA
AGVKEHVVNI AKLSAAVDVV KTREVHPVDV ESPPAEAPPE EDDKAAAATA AAVAGAGEKK
VAA
