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SWT15_ORYSI
ID   SWT15_ORYSI             Reviewed;         319 AA.
AC   A2X5B4;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Bidirectional sugar transporter SWEET15;
DE            Short=OsSWEET15;
GN   Name=SWEET15; ORFNames=OsI_07385;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC       the plasma membrane. {ECO:0000250|UniProtKB:Q8L9J7}.
CC   -!- SUBUNIT: Forms homooligomers and/or heterooligomers.
CC       {ECO:0000250|UniProtKB:Q8L9J7}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8L9J7};
CC       Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
CC   -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC       {ECO:0000305}.
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DR   EMBL; CM000127; EAY86024.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2X5B4; -.
DR   SMR; A2X5B4; -.
DR   STRING; 39946.A2X5B4; -.
DR   EnsemblPlants; BGIOSGA006395-TA; BGIOSGA006395-PA; BGIOSGA006395.
DR   Gramene; BGIOSGA006395-TA; BGIOSGA006395-PA; BGIOSGA006395.
DR   HOGENOM; CLU_048643_4_0_1; -.
DR   OMA; ERSTWAF; -.
DR   Proteomes; UP000007015; Chromosome 2.
DR   GO; GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB.
DR   GO; GO:0051119; F:sugar transmembrane transporter activity; ISS:UniProtKB.
DR   InterPro; IPR004316; SWEET_sugar_transpr.
DR   Pfam; PF03083; MtN3_slv; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..319
FT                   /note="Bidirectional sugar transporter SWEET15"
FT                   /id="PRO_0000404150"
FT   TOPO_DOM        1..10
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        11..31
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        32..50
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..71
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        72
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        94..106
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        128..134
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        156..167
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        189..191
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        213..319
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          13..99
FT                   /note="MtN3/slv 1"
FT   DOMAIN          135..219
FT                   /note="MtN3/slv 2"
SQ   SEQUENCE   319 AA;  34924 MW;  E25D6386A1ECD713 CRC64;
     MAFMSMERST WAFTFGILGN LISLMVFLSP LPTFYRVYRK KSTEGFQSTP YVVTLFSCML
     WMYYAFVKSG AELLVTINGV GCVIETVYLA MYLAYAPKSA RMLTAKMLLG LNIGLFGVIA
     LVTLLLSRGE LRVHVLGWIC VAVSLSVFAA PLSIIRLVIR TKSVEFMPFS LSFFLVLSAV
     IWFLYGLLKK DVFVALPNVL GFVFGVAQMA LYMAYRSKKP LVASSSSAAV AAGLETKLPE
     HVKEVQAVAK GAVAAAPEGR ISCGAEVHPI DDVMPSEVVE VKVDDEETNR TDEMAGDGDH
     AMVRTEQIIK PDMAIVVEV
 
 
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