SWT15_VITVI
ID SWT15_VITVI Reviewed; 289 AA.
AC P0DKJ5;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2015, sequence version 1.
DT 03-AUG-2022, entry version 26.
DE RecName: Full=Bidirectional sugar transporter SWEET15 {ECO:0000305};
DE Short=VvSWEET15 {ECO:0000305};
GN Name=SWEET15 {ECO:0000305};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024;
RX PubMed=17721507; DOI=10.1038/nature06148;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the plasma membrane. {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SUBUNIT: Forms homooligomers and/or heterooligomers.
CC {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8L9J7};
CC Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000305}.
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DR EMBL; FN597015; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_002264875.1; XM_002264839.3.
DR AlphaFoldDB; P0DKJ5; -.
DR SMR; P0DKJ5; -.
DR EnsemblPlants; Vitvi01g01719_t001; Vitvi01g01719_P001; Vitvi01g01719.
DR GeneID; 100243643; -.
DR Gramene; Vitvi01g01719_t001; Vitvi01g01719_P001; Vitvi01g01719.
DR KEGG; vvi:100243643; -.
DR OMA; ISINDHV; -.
DR OrthoDB; 1116261at2759; -.
DR Proteomes; UP000009183; Chromosome 1.
DR ExpressionAtlas; P0DKJ5; baseline and differential.
DR GO; GO:0000139; C:Golgi membrane; IEA:EnsemblPlants.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:EnsemblPlants.
DR GO; GO:0008515; F:sucrose transmembrane transporter activity; IEA:EnsemblPlants.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR GO; GO:0071215; P:cellular response to abscisic acid stimulus; IEA:EnsemblPlants.
DR GO; GO:0071470; P:cellular response to osmotic stress; IEA:EnsemblPlants.
DR GO; GO:0071446; P:cellular response to salicylic acid stimulus; IEA:EnsemblPlants.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IEA:EnsemblPlants.
DR GO; GO:0010150; P:leaf senescence; IEA:EnsemblPlants.
DR GO; GO:0010431; P:seed maturation; IEA:EnsemblPlants.
DR InterPro; IPR004316; SWEET_sugar_transpr.
DR Pfam; PF03083; MtN3_slv; 2.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Repeat; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..289
FT /note="Bidirectional sugar transporter SWEET15"
FT /id="PRO_0000434110"
FT TOPO_DOM 1..10
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 11..31
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 32..45
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 46..66
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 67..70
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 71..91
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 92..106
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 107..127
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 128..134
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 135..155
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 156..167
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 168..188
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 189..193
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 194..214
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 215..289
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT DOMAIN 14..100
FT /note="MtN3/slv 1"
FT /evidence="ECO:0000305"
FT DOMAIN 136..219
FT /note="MtN3/slv 2"
FT /evidence="ECO:0000305"
FT REGION 249..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 289 AA; 32149 MW; B7ADFBD824AE0736 CRC64;
MAMAMANHHT LGLIFGILGN IISFLVYFAP APTFYRIYKR KSAEGFHSLP YIVALFSAML
WLYYALLKKD AFLLITINSF GCAIESFYIL LYFFYAPMQA KKQTLKVVIS LNVGVFSILV
VLIQFLLKGS NRINVFGWIC ASFSVAVFAA PLSIVAKVIR TKSVEFMPFS LSFFLTLSAI
MWFAYGLLKN DPCVAIPNIL GVILGLVQMV LYGFYRNAGK EKMEKKLPEH IIDMVMLSTL
GTSDIHPIGA QQNGIKKSGS EDVKDDEETG NREKSTENSG ELQPNGSTV
