SWT1_SCHPO
ID SWT1_SCHPO Reviewed; 465 AA.
AC Q9P7J1;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2012, sequence version 2.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Transcriptional protein swt1;
GN Name=swt1 {ECO:0000250|UniProtKB:Q12104}; ORFNames=SPCC24B10.15;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP REVISION OF GENE MODEL.
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
RN [3] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Involved in transcription. {ECO:0000250|UniProtKB:Q12104}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the SWT1 family. {ECO:0000305}.
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DR EMBL; CU329672; CAB76224.2; -; Genomic_DNA.
DR PIR; T50422; T50422.
DR RefSeq; NP_588018.2; NM_001023009.2.
DR AlphaFoldDB; Q9P7J1; -.
DR SMR; Q9P7J1; -.
DR BioGRID; 275465; 1.
DR STRING; 4896.SPCC24B10.15.1; -.
DR MaxQB; Q9P7J1; -.
DR PaxDb; Q9P7J1; -.
DR PRIDE; Q9P7J1; -.
DR EnsemblFungi; SPCC24B10.15.1; SPCC24B10.15.1:pep; SPCC24B10.15.
DR PomBase; SPCC24B10.15; swt1.
DR VEuPathDB; FungiDB:SPCC24B10.15; -.
DR eggNOG; KOG4689; Eukaryota.
DR HOGENOM; CLU_046583_0_0_1; -.
DR InParanoid; Q9P7J1; -.
DR OMA; YIHWYTC; -.
DR PRO; PR:Q9P7J1; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0004521; F:endoribonuclease activity; ISO:PomBase.
DR GO; GO:0010467; P:gene expression; IEA:UniProt.
DR GO; GO:0071032; P:nuclear mRNA surveillance of mRNP export; ISO:PomBase.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR Pfam; PF13638; PIN_4; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF88723; SSF88723; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome; Transcription.
FT CHAIN 1..465
FT /note="Transcriptional protein swt1"
FT /id="PRO_0000353139"
FT DOMAIN 70..190
FT /note="PINc"
SQ SEQUENCE 465 AA; 52734 MW; DE967A67C2F07C9B CRC64;
MDRMEIDDQA GIDFVTESIN SERARNRWST SHIPSLSEIN PSSFQSPSPS PFASSTSLAS
KPARYSKPLG LFVLDTNFLL SHLSLCQNLI EFLTARCPRL VVVLPWTVLQ ELDGLKSESS
STCGYLARQA HNFLLQCFRS NVSSLRGQKV HEHCSSTEKG DDAILDCCIY YQEEKLIPAV
LLSDDKNLSI KAAVHHIQSL SFSKGLEAAS IVQTSFPSAF SSNSENLENL SMDIDLTVSQ
PLATATNHRN QGASTVDIPM DRTHDNSIWA SRYAHFPPYD KKKDTTRSAA DYIPYTYTAL
TKEEILHASH PRACKLLDQI TKIMVEETAF LLSRHLLKLW GDYDLAMTKL LASPQFPPQN
INDVGHELYI HWYTCFDGYL PAQERSNLKS KAELWNEWML WAERGIGIGP KNQEELQTYV
TFWSNIWTLL SRREILGDQA STYIGFREQN IEKWVERSGR ERILS
