ID   SWT21_ASHGO             Reviewed;         407 AA.
AC   Q75E79;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Protein SWT21;
GN   Name=SWT21; OrderedLocusNames=ABL147W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in mRNA splicing. Helps to stabilize the U1 snRNP-5'
CC       splice site interaction (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with snRNPs. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWT21 family. {ECO:0000305}.
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DR   EMBL; AE016815; AAS50624.1; -; Genomic_DNA.
DR   RefSeq; NP_982800.1; NM_208153.1.
DR   AlphaFoldDB; Q75E79; -.
DR   STRING; 33169.AAS50624; -.
DR   EnsemblFungi; AAS50624; AAS50624; AGOS_ABL147W.
DR   GeneID; 4618880; -.
DR   KEGG; ago:AGOS_ABL147W; -.
DR   eggNOG; ENOG502QVPI; Eukaryota.
DR   HOGENOM; CLU_662333_0_0_1; -.
DR   InParanoid; Q75E79; -.
DR   OMA; DYGIRQY; -.
DR   Proteomes; UP000000591; Chromosome II.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT   CHAIN           1..407
FT                   /note="Protein SWT21"
FT                   /id="PRO_0000405682"
SQ   SEQUENCE   407 AA;  45512 MW;  C23F30E42F943279 CRC64;
     MNILAHTGDI FHGRGKLHAS LKEQQVWDDL RRPGHDVPQL PRPQGYTASQ PIYKRLPVVC
     RGLTWSFDGS SLVAVHEDCG IRQYAVCEEQ GPVMAPVQRF FKPQAIISHA VHPQNSLFQA
     DSSLNVVVVS CKDMPYQLYP LHSNPDQPAR ALQTYNSASE STEEFRAAYA MDFLDDAHFL
     AGSTRNTVSL FDASRRESIW VSSATRRGCG RGQHKAIVSC FDEANERRDC VRYAGTYRSE
     LLRIDPRTSS ISSWKAIQDK SRGIYQVLQS NNGHYFYIMK RYSNSITVLD SRKSMAIVNQ
     FKLPFQTHAQ KLRGTYSTRH GLLIGDEAGR ILQWAPEVVE FGGIDRSGSV PSYGIGETGI
     THVCAEGSRI NIIEKNPADS DIFAISYSPD KYGEDVSCNA GILLMRL