ID   SWT21_CANGA             Reviewed;         419 AA.
AC   Q6FNI6;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Protein SWT21;
GN   Name=SWT21; OrderedLocusNames=CAGL0J11396g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in mRNA splicing. Helps to stabilize the U1 snRNP-5'
CC       splice site interaction (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with snRNPs. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWT21 family. {ECO:0000305}.
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DR   EMBL; CR380956; CAG61159.1; -; Genomic_DNA.
DR   RefSeq; XP_448208.1; XM_448208.1.
DR   AlphaFoldDB; Q6FNI6; -.
DR   STRING; 5478.XP_448208.1; -.
DR   EnsemblFungi; CAG61159; CAG61159; CAGL0J11396g.
DR   GeneID; 2889524; -.
DR   KEGG; cgr:CAGL0J11396g; -.
DR   CGD; CAL0133758; CAGL0J11396g.
DR   VEuPathDB; FungiDB:CAGL0J11396g; -.
DR   eggNOG; ENOG502QVPI; Eukaryota.
DR   HOGENOM; CLU_662333_0_0_1; -.
DR   InParanoid; Q6FNI6; -.
DR   OMA; DYGIRQY; -.
DR   Proteomes; UP000002428; Chromosome J.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT   CHAIN           1..419
FT                   /note="Protein SWT21"
FT                   /id="PRO_0000405683"
SQ   SEQUENCE   419 AA;  47346 MW;  32E24094225AE78B CRC64;
     MNQANVKNTT FHSMTSVSYN LSPYCSTGTT FRKQPLYRIW ETESSTSADL SQKLNYMFPK
     LGLSESQTSL KDKDVTKDVV CQDIHWSVDA TSLFTINSDY GIRQYLIPDP KSDQTLLNPY
     SRIFAHESVL SSDISPRYSL YEGSSEPLAN SILIGAKNVP IKLVDLNDTN NLSTIRSYDI
     SNLENEKFET PYVLKYHRES LFLSGTVRNK VNVYDVNRRE PVNTLTYSRR SKCGTQSYKS
     IISCLDDSFS DNQVRYCGSY KNQVFIIDLR GKTLQLLNNL QGNGARGCYQ IINSDNGSYL
     YVLQRYSSRI EILDHRRPDR PVNHLELPGR SDFQKLKACY NGSFQVGSPL GKGQILSWDK
     STIESGGITR ENQVVQCQPD ILYNVPQCKS MRINIIKTSS DATAISYSGD TAGIALLQR