ID   SWT21_YEAS7             Reviewed;         357 AA.
AC   A6ZRQ0;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Protein SWT21;
DE   AltName: Full=Synthetic With TGS1 protein 21;
GN   Name=SWT21; ORFNames=SCY_4611;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Involved in mRNA splicing. Helps to stabilize the U1 snRNP-5'
CC       splice site interaction (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associates with snRNPs. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SWT21 family. {ECO:0000305}.
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DR   EMBL; AAFW02000067; EDN62632.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZRQ0; -.
DR   EnsemblFungi; EDN62632; EDN62632; SCY_4611.
DR   HOGENOM; CLU_662333_0_0_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus.
FT   CHAIN           1..357
FT                   /note="Protein SWT21"
FT                   /id="PRO_0000405690"
SQ   SEQUENCE   357 AA;  40308 MW;  ED52B00C4902453A CRC64;
     MEKKVICQDI FWSCDGTSFV SVHNDFGIRQ YLVPEESNTD KLNRNLLLPF TRFFRNQSIV
     SCAIDPFYTL YNENSDRLAG DRIVVGGKNF PLQLYSLMDG QCILSYDTMN KINGEYETVY
     SVKIDVESRV YTGSCRNKVA IYDKSRRDAV WMNQSTKKAS KGRQSIISCF EEQPMGGQAL
     SRGSLLCGSY ANEMFQVDCR HQRLERLNYT RTVAGGIVQI LTSDNGRYVY VVRRNSDAIS
     IYDRRNLQHE LNVLRLPFRI HHNSAKLKAY IDTAYGLSMG TPQGTILNWG RDLVEFGGVP
     SHNSVEDPLI TSIPPESEWR TNLDSTIPAT VVKNCPGDPE LFALSHGGTI SLCRFGG