SWT6A_ORYSI
ID SWT6A_ORYSI Reviewed; 259 AA.
AC A2WSD8;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Bidirectional sugar transporter SWEET6a;
DE Short=OsSWEET6a;
GN Name=SWEET6A; ORFNames=OsI_02773;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the plasma membrane. {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SUBUNIT: Forms homooligomers and/or heterooligomers.
CC {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8L9J7};
CC Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM000126; EAY74884.1; -; Genomic_DNA.
DR AlphaFoldDB; A2WSD8; -.
DR SMR; A2WSD8; -.
DR STRING; 39946.A2WSD8; -.
DR EnsemblPlants; BGIOSGA003951-TA; BGIOSGA003951-PA; BGIOSGA003951.
DR Gramene; BGIOSGA003951-TA; BGIOSGA003951-PA; BGIOSGA003951.
DR HOGENOM; CLU_048643_1_0_1; -.
DR OMA; LWLIGEM; -.
DR Proteomes; UP000007015; Chromosome 1.
DR GO; GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; ISS:UniProtKB.
DR InterPro; IPR004316; SWEET_sugar_transpr.
DR Pfam; PF03083; MtN3_slv; 2.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Repeat; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..259
FT /note="Bidirectional sugar transporter SWEET6a"
FT /id="PRO_0000404143"
FT TOPO_DOM 1..9
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 10..30
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 31..45
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 46..66
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 67..69
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 91..103
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..124
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 125..131
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 132..152
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 153..165
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 166..186
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 187..189
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 211..259
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 10..98
FT /note="MtN3/slv 1"
FT DOMAIN 133..216
FT /note="MtN3/slv 2"
SQ SEQUENCE 259 AA; 28184 MW; 5BB1DBFC70988054 CRC64;
MISPDAARNV VGIIGNVISF GLFLAPVPTF WRICKRKDVE EFKADPYLAT LLNCMLWVFY
GIPVVHPNSI LVVTINGIGL LVEGTYLLIF FLYSPNKKRL RMCAVLGVEL VFMLAVILGV
LLGAHTHEKR SMIVGILCVF FGSIMYFSPL TIMGKVIKTK SVEYMPFFLS LVCFLNGVCW
TAYALIRFDI YVTIPNGLGA LFGAIQLILY ACYYRTTPKK TKAAKDVEMP SVVVSGTGAA
AAAGGGNTGG GSISVTVER
