ID   SWT7C_ORYSI             Reviewed;         240 AA.
AC   A2ZIM4;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Bidirectional sugar transporter SWEET7c;
DE            Short=OsSWEET7c;
GN   Name=SWEET7C; ORFNames=OsI_37675;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC       the plasma membrane. {ECO:0000250|UniProtKB:Q8L9J7}.
CC   -!- SUBUNIT: Forms homooligomers and/or heterooligomers.
CC       {ECO:0000250|UniProtKB:Q8L9J7}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q8L9J7};
CC       Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
CC   -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM000137; EAY82458.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2ZIM4; -.
DR   SMR; A2ZIM4; -.
DR   EnsemblPlants; BGIOSGA037095-TA; BGIOSGA037095-PA; BGIOSGA037095.
DR   Gramene; BGIOSGA037095-TA; BGIOSGA037095-PA; BGIOSGA037095.
DR   HOGENOM; CLU_048643_1_0_1; -.
DR   OMA; FIICAAK; -.
DR   Proteomes; UP000007015; Chromosome 12.
DR   GO; GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB.
DR   GO; GO:0051119; F:sugar transmembrane transporter activity; ISS:UniProtKB.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004316; SWEET_sugar_transpr.
DR   Pfam; PF03083; MtN3_slv; 2.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Glycoprotein; Membrane; Reference proteome; Repeat;
KW   Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..240
FT                   /note="Bidirectional sugar transporter SWEET7c"
FT                   /id="PRO_0000404146"
FT   TOPO_DOM        1..12
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        13..33
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        34..46
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        68..78
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        79..99
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        100..108
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        130..140
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        162..164
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..185
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        186..240
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          10..48
FT                   /note="MtN3/slv 1"
FT   DOMAIN          110..191
FT                   /note="MtN3/slv 2"
FT   CARBOHYD        225
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        235
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   240 AA;  26358 MW;  80CEC9CF7AD823CE CRC64;
     MVSPDLIRNV VGIVGNVISF GLFLSPVPIF WWIIKNKNVQ NFKADPILVV TINGISLVIE
     AVYLTIFFLF SDKKNKKKMG VVLATEALFM AAVAVGVLLG AHTHQRRSLI VGILCVIFGT
     IMYSSPLTIM VVKTKSVEYM PLLLSVVSFL NGLCWTLYAL IRFDIFITIP NGLGVLFAIM
     QLILYAIYYR TTPKKQDKNL ELPTVAPIAK DTSIVAPVGN DDDVNGSTAS HATINITIEP