ID   ABITM_XENTR             Reviewed;         183 AA.
AC   Q28G67; Q6DIQ7;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Protein Abitram {ECO:0000305};
DE   AltName: Full=Actin-binding transcription modulator;
DE   AltName: Full=Protein Simiate;
GN   Name=abitram; Synonyms=fam206a; ORFNames=TGas009a04.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May regulate actin polymerization, filopodia dynamics and
CC       arborization of neurons. {ECO:0000250|UniProtKB:Q80ZQ9}.
CC   -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000250|UniProtKB:Q80ZQ9}.
CC       Cell projection, lamellipodium {ECO:0000250|UniProtKB:Q80ZQ9}. Nucleus
CC       {ECO:0000250|UniProtKB:Q80ZQ9}. Cell projection, growth cone
CC       {ECO:0000250|UniProtKB:Q80ZQ9}. Cell projection, dendrite
CC       {ECO:0000250|UniProtKB:Q80ZQ9}. Note=Localizes to somata and dendrites
CC       in cortical neurons. {ECO:0000250|UniProtKB:Q80ZQ9}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q28G67-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q28G67-2; Sequence=VSP_026315;
CC   -!- SIMILARITY: Belongs to the ABITRAM family. {ECO:0000305}.
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DR   EMBL; CR761531; CAJ82750.1; -; mRNA.
DR   EMBL; BC075478; AAH75478.1; -; mRNA.
DR   RefSeq; NP_001004966.1; NM_001004966.1. [Q28G67-2]
DR   RefSeq; XP_012819979.1; XM_012964525.2. [Q28G67-2]
DR   RefSeq; XP_012819980.1; XM_012964526.2. [Q28G67-1]
DR   RefSeq; XP_012819981.1; XM_012964527.2. [Q28G67-1]
DR   AlphaFoldDB; Q28G67; -.
DR   SMR; Q28G67; -.
DR   GeneID; 448390; -.
DR   KEGG; xtr:448390; -.
DR   CTD; 54942; -.
DR   Xenbase; XB-GENE-6458491; abitram.
DR   InParanoid; Q28G67; -.
DR   OMA; CCMIGKL; -.
DR   OrthoDB; 1277002at2759; -.
DR   TreeFam; TF313930; -.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000027667; Expressed in ovary and 16 other tissues.
DR   GO; GO:0030425; C:dendrite; IBA:GO_Central.
DR   GO; GO:0032433; C:filopodium tip; ISS:UniProtKB.
DR   GO; GO:0030426; C:growth cone; ISS:UniProtKB.
DR   GO; GO:0030027; C:lamellipodium; ISS:UniProtKB.
DR   GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR   GO; GO:0003785; F:actin monomer binding; IBA:GO_Central.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.
DR   InterPro; IPR039169; Abitram.
DR   InterPro; IPR033753; GCV_H/Fam206.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR13651; PTHR13651; 1.
DR   Pfam; PF01597; GCV_H; 1.
DR   SUPFAM; SSF51230; SSF51230; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Cell projection; Nucleus; Reference proteome.
FT   CHAIN           1..183
FT                   /note="Protein Abitram"
FT                   /id="PRO_0000291934"
FT   VAR_SEQ         86
FT                   /note="R -> RGRPFIFQQDNARPHSASITTSWLRRRRIRVLKWPVCSPDLSPIENI
FT                   WHIIQRK (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.2"
FT                   /id="VSP_026315"
SQ   SEQUENCE   183 AA;  20585 MW;  14D623534B8D790C CRC64;
     MAEECNKLLE FPSVVDRYFK RWYKSDVKGK PCEDHCILQH SNRICIITLA ECHPLLQNGK
     TIKTISYQIS ANCSRLQNKV SGKSKRGAQF LTEHAPLCRI SSTDGEEYTI YSCIRGRLLE
     VNENILQNPE LLKEKPSTEG YIAVVLPKFE ESKTVTEGLL SQQEYEEILL SRAAVGSGTV
     SAV