ABI_ECOLX
ID ABI_ECOLX Reviewed; 89 AA.
AC P18024;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1990, sequence version 1.
DT 03-AUG-2022, entry version 47.
DE RecName: Full=Abortive infection protein;
GN Name=abi;
OS Escherichia coli.
OG Plasmid IncI1 ColIb.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3072577; DOI=10.1016/0147-619x(88)90026-1;
RA Gupta S.K., McCorquodale D.J.;
RT "Nucleotide sequence of a DNA fragment that contains the abi gene of the
RT ColIb plasmid.";
RL Plasmid 20:194-206(1988).
CC -!- FUNCTION: ABI may interact with a target in the cell membrane, which
CC could be the product of the host's cmrA gene, and cause disruption of
CC the cellular membrane such that lysis of the infected cell and death of
CC the infecting phage would result.
CC -!- SUBCELLULAR LOCATION: Cell membrane. Note=This very hydrophobic protein
CC could insert itself into membranes.
CC -!- MISCELLANEOUS: When phage T5 or its close relative BF23, infects cells
CC harboring a ColIb plasmid, the infection is abortive. The mechanism
CC involves gene products from the phage, the ColIb plasmid, and the host.
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DR EMBL; J03314; AAA23185.1; -; Genomic_DNA.
DR EMBL; M36875; AAA23186.1; -; Genomic_DNA.
DR PIR; I40752; I40752.
DR AlphaFoldDB; P18024; -.
DR SMR; P18024; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE 4: Predicted;
KW Cell membrane; Membrane; Plasmid.
FT CHAIN 1..89
FT /note="Abortive infection protein"
FT /id="PRO_0000068346"
SQ SEQUENCE 89 AA; 10122 MW; 3985618E6CC75AC2 CRC64;
MTKIKTVTFV NTYPGGSMKN LLDTEGTVLF PFQTEIHFIW TIFSTVKRLV IGTRDHICQK
QYWSACLCIL LLMAYVGLCA AVVWFVVPC