ID   SYB_TETCF               Reviewed;         120 AA.
AC   P13701;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Synaptobrevin;
DE   AltName: Full=Synaptic vesicle-associated integral membrane protein;
DE   AltName: Full=VAMP-1;
OS   Tetronarce californica (Pacific electric ray) (Torpedo californica).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Batoidea; Torpediniformes; Torpedinidae; Tetronarce.
OX   NCBI_TaxID=7787;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3380805; DOI=10.1073/pnas.85.12.4538;
RA   Trimble W.S., Cowen D.M., Scheller R.H.;
RT   "VAMP-1: a synaptic vesicle-associated integral membrane protein.";
RL   Proc. Natl. Acad. Sci. U.S.A. 85:4538-4542(1988).
CC   -!- FUNCTION: This protein may play a role in packaging, transport or
CC       release of neurotransmitters.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic
CC       vesicle membrane; Single-pass type IV membrane protein. Synapse,
CC       synaptosome. Note=Neuronal synaptic vesicles.
CC   -!- TISSUE SPECIFICITY: Nervous system specific.
CC   -!- SIMILARITY: Belongs to the synaptobrevin family. {ECO:0000305}.
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DR   EMBL; J03777; AAA49286.1; -; mRNA.
DR   PIR; A32146; A32146.
DR   AlphaFoldDB; P13701; -.
DR   SMR; P13701; -.
DR   GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043005; C:neuron projection; IEA:UniProtKB-KW.
DR   GO; GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR001388; Synaptobrevin.
DR   InterPro; IPR016444; Synaptobrevin/VAMP.
DR   InterPro; IPR042855; V_SNARE_CC.
DR   PANTHER; PTHR45701; PTHR45701; 1.
DR   Pfam; PF00957; Synaptobrevin; 1.
DR   PIRSF; PIRSF005409; Synaptobrevin_euk; 1.
DR   PRINTS; PR00219; SYNAPTOBREVN.
DR   PROSITE; PS00417; SYNAPTOBREVIN; 1.
DR   PROSITE; PS50892; V_SNARE; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasmic vesicle; Membrane; Synapse; Synaptosome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..120
FT                   /note="Synaptobrevin"
FT                   /id="PRO_0000206743"
FT   TOPO_DOM        1..98
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..118
FT                   /note="Helical; Anchor for type IV membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        119..120
FT                   /note="Vesicular"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          35..95
FT                   /note="v-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00290"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   120 AA;  12979 MW;  D430AEE0A6F4A1AB CRC64;
     MSAPPSGPAP DAQGGAPGQP TGPPGAPPNT TSNRRLQQTQ AQVEEVVDII RVNVDKVLER
     DQKLSELDDR ADALQAGASQ FESSAAKLKR KYWWKNCKMM IMLGGIGAII VIVIIIYFFT