ID   SYCN_YEREN              Reviewed;         123 AA.
AC   P0C2V8; P16162; Q52095; Q93KT9;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Chaperone protein SycN;
GN   Name=sycN;
OS   Yersinia enterocolitica.
OG   Plasmid pYV, Plasmid pYVe227, and Plasmid pYVa127/90.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serotype O:3; PLASMID=pYV;
RX   PubMed=2160939; DOI=10.1128/jb.172.6.3152-3162.1990;
RA   Viitanen A.-M., Toivanen P., Skurnik M.;
RT   "The lcrE gene is part of an operon in the lcr region of Yersinia
RT   enterocolitica O:3.";
RL   J. Bacteriol. 172:3152-3162(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=W22703 / Serotype O:9 / Biotype 2; PLASMID=pYVe227;
RA   Iriarte M., Lambermont I., Kerbourch C., Cornelis G.R.;
RT   "Detailed genetic map of the pYVe227 plasmid of Yersinia enterocolitica
RT   serotype O:9.";
RL   Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A127/90 / Serotype O:8 / Biotype 1B; PLASMID=pYVa127/90;
RX   PubMed=14527656; DOI=10.1016/s0923-2508(03)00147-5;
RA   Foultier B., Cornelis G.R.;
RT   "DNA sequence and analysis of the pYVa127/90 virulence plasmid of Yersinia
RT   enterocolitica strain A127/90.";
RL   Res. Microbiol. 154:553-557(2003).
RN   [4]
RP   FUNCTION.
RC   PLASMID=pYV;
RX   PubMed=9882687; DOI=10.1128/jb.181.2.675-680.1999;
RA   Iriarte M., Cornelis G.R.;
RT   "Identification of SycN, YscX, and YscY, three new elements of the Yersinia
RT   Yop virulon.";
RL   J. Bacteriol. 181:675-680(1999).
RN   [5]
RP   FUNCTION, AND SUBUNIT.
RC   STRAIN=W22703 / Serotype O:9 / Biotype 2;
RX   PubMed=11514512; DOI=10.1128/jb.183.18.5293-5301.2001;
RA   Cheng L.W., Kay O., Schneewind O.;
RT   "Regulated secretion of YopN by the type III machinery of Yersinia
RT   enterocolitica.";
RL   J. Bacteriol. 183:5293-5301(2001).
CC   -!- FUNCTION: Functions as a specific chaperone for YopN. It could
CC       facilitate the secretion and the subsequent translocation of YopN.
CC       {ECO:0000269|PubMed:11514512, ECO:0000269|PubMed:9882687}.
CC   -!- SUBUNIT: Interacts with YscB to form a complex which specifically binds
CC       to YopN. {ECO:0000269|PubMed:11514512}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell inner membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Not
CC       exported across the inner membrane. {ECO:0000250}.
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DR   EMBL; M32097; AAA98431.1; -; Genomic_DNA.
DR   EMBL; AF102990; AAD16821.1; -; Genomic_DNA.
DR   EMBL; AY150843; AAN37520.1; -; Genomic_DNA.
DR   PIR; C35392; C35392.
DR   RefSeq; NP_052398.1; NC_002120.1.
DR   RefSeq; NP_783671.1; NC_004564.1.
DR   RefSeq; NP_863520.1; NC_005017.1.
DR   RefSeq; WP_005176811.1; NZ_NWMR01000033.1.
DR   RefSeq; WP_010891215.1; NZ_SJZK01000009.1.
DR   AlphaFoldDB; P0C2V8; -.
DR   SMR; P0C2V8; -.
DR   PATRIC; fig|630.129.peg.4359; -.
DR   OrthoDB; 1592725at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   InterPro; IPR012673; T3SS_SynN.
DR   TIGRFAMs; TIGR02503; type_III_SycN; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Chaperone; Cytoplasm; Membrane;
KW   Plasmid.
FT   CHAIN           1..123
FT                   /note="Chaperone protein SycN"
FT                   /id="PRO_0000072359"
FT   VARIANT         58
FT                   /note="Q -> R (in plasmid pYVa127/90)"
FT   VARIANT         77
FT                   /note="A -> T (in plasmid pYVa127/90)"
FT   VARIANT         88
FT                   /note="N -> S (in plasmid pYVa127/90)"
SQ   SEQUENCE   123 AA;  13608 MW;  37732AA55A3FF9AD CRC64;
     MSWIEPIISH FCQDLGVPTS SPLSPLIQLE MAQSGTLQLE QHGATLTLWL ARSLAWHQCE
     DAMVKALTLT AAQKSGALPL RAGWLGENQL VLFVSLDERS LTLPLLHQAF EQLLRLQQEV
     LAP