SYCP1_ARATH
ID SYCP1_ARATH Reviewed; 871 AA.
AC Q9LME2; Q4TWG2;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Synaptonemal complex protein 1;
DE AltName: Full=Synaptonemal complex central region protein ZYP1a;
GN Name=ZYP1A; OrderedLocusNames=At1g22260; ORFNames=T16E15.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16230536; DOI=10.1101/gad.354705;
RA Higgins J.D., Sanchez-Moran E., Armstrong S.J., Jones G.H., Franklin F.C.;
RT "The Arabidopsis synaptonemal complex protein ZYP1 is required for
RT chromosome synapsis and normal fidelity of crossing over.";
RL Genes Dev. 19:2488-2500(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Required for chromosome synapsis and normal fidelity of
CC crossing over.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; DQ028764; AAY46119.1; -; mRNA.
DR EMBL; AC068562; AAF87265.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30217.1; -; Genomic_DNA.
DR PIR; D86355; D86355.
DR RefSeq; NP_173645.3; NM_102076.4.
DR AlphaFoldDB; Q9LME2; -.
DR SMR; Q9LME2; -.
DR STRING; 3702.AT1G22260.1; -.
DR PaxDb; Q9LME2; -.
DR PRIDE; Q9LME2; -.
DR EnsemblPlants; AT1G22260.1; AT1G22260.1; AT1G22260.
DR GeneID; 838831; -.
DR Gramene; AT1G22260.1; AT1G22260.1; AT1G22260.
DR KEGG; ath:AT1G22260; -.
DR Araport; AT1G22260; -.
DR TAIR; locus:2015031; AT1G22260.
DR eggNOG; ENOG502QSSX; Eukaryota.
DR HOGENOM; CLU_010415_0_0_1; -.
DR InParanoid; Q9LME2; -.
DR OMA; GNNEYAK; -.
DR OrthoDB; 251210at2759; -.
DR PhylomeDB; Q9LME2; -.
DR PRO; PR:Q9LME2; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LME2; baseline and differential.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0000795; C:synaptonemal complex; IDA:TAIR.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007129; P:homologous chromosome pairing at meiosis; IMP:TAIR.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IMP:TAIR.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Coiled coil; Meiosis; Nucleus;
KW Reference proteome.
FT CHAIN 1..871
FT /note="Synaptonemal complex protein 1"
FT /id="PRO_0000220590"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 708..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 778..871
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 58..304
FT /evidence="ECO:0000255"
FT COILED 331..608
FT /evidence="ECO:0000255"
FT COMPBIAS 16..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..732
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..826
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 827..850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 871 AA; 100007 MW; E8D2778FF98CBE54 CRC64;
MQKLGFPAMK SLDKPRSLSG SANMYSFSNR KPPDSVSSGS FSNLKLTAEK LVKDQAAMRT
DLELANCKLK KSMEHVYALE EKLQNAFNEN AKLRVRKKED EKLWRGLESK FSSTKTLCDQ
LTETLQHLAS QVQDAEKDKG FFETKFSTSS EAIDSLNQQM RDMSLRLDAA KEEITSRDKE
LEELKLEKQQ KEMFYQTERC GTASLIEKKD AVITKLEASA AERKLNIENL NSQLEKVHLE
LTTKEDEVKD LVSIQEKLEK EKTSVQLSAD NCFEKLVSSE QEVKKLDELV QYLVAELTEL
DKKNLTFKEK FDKLSGLYDT HIMLLQKDRD LALDRAQRSF DNLQGELFRV AATKEALESA
GNELNEKIVE LQNDKESLIS QLSGLRCSTS QTIDKLESEA KGLVSKHADA ESAISQLKEE
METLLESVKT SEDKKQELSL KLSSLEMESK EKCEKLQADA QRQVEELETL QKESESHQLQ
ADLLAKEVNQ LQTVIEEKGH VILQCNENEK QLNQQIIKDK ELLATAETKL AEAKKQYDLM
LESKQLELSR HLKELSQRND QAINEIRRKY DVEKHEIINS EKDKVEKIIK DLSNKFDKEL
SDCKEESKRQ LLTIQEEHSS LILSLREEHE SKELNLKAKY DQELRQSQIQ AENELKERIT
ALKSEHDAQL KAFKCQYEDD CKKLQEELDL QRKKEERQRA LVQLQWKVMS DNPPEEQEVN
SNKNYSISKD SRLGGSKRSE HIRVRSDNDN VQDSPFVKAK ETPVSKILKK AQNVNAGSVL
SIPNPKHHSK VTHREYEVET NNGRVTKRRK TRNTTMFEEP QRRRTRATPK LTPQSIAKGT
GMTSHARSAN IGDLFSEGSL NPYADDPYAF D
